Chemical #priming of #hypoxia responses via PLANT #CYSTEINE OXIDASE inhibition improves #flooding tolerance

academic.oup.com/plphys/artic...

#PlantScience @plantphys.bsky.social @aspbofficial.bsky.social @planteditors.bsky.social @isplore.bsky.social @plant-sci.bsky.social @sciplant.bsky.social

Study identifies backup pathway that lets cells make cysteine without major disulfide reductases

#cellbiology #cysteine #metabolism #cancer

Why is #cysteine amino acid so toxic to cells?

www.rockefeller.edu/news/40469-c...

— intracellular cysteine stored as glutathione
— excess cysteine frees iron from ferritin
— excess iron in mitochondria damages iron-sulfur proteins
— mitochondria fail
— cell death

#health #supplement #aging