@rom12relle.bsky.social @johnlees.bacpop.org & Chindelevitch present kamino, a reference- and alignment-free method that rapidly builds amino acid phylogenomic alignments directly from proteomes.

@rom12relle.bsky.social @johnlees.bacpop.org & Chindelevitch present kamino, a reference- and alignment-free method that rapidly builds amino acid phylogenomic alignments directly from proteomes.
Two PhD positions open in my group @ethz.ch (Basel):
Digital twins of embryonic development.
𧬠Mathematical modelling of biology jobs.ethz.ch/job/view/JOP...
π» Computing: parameter estimation (incl. PINNs), simulation environments jobs.ethz.ch/job/view/JOP...
We have developed Ciclopes, a biology-informed deep-learning framework that uses an autoencoder to reconstruct periodic gene expression dynamics and estimates phase-dependent transcription and degradation rates #CompBio, #DeepLearning, #MechansticModelling, #scRNAseq.
From individual thresholds to collective hysteresis: a mechanistic model of the dawn chorus: buff.ly/gtVWLSq #JRSocInterface #CompBio
Paired germline and tumor sequencing data from 1,110 colorectal or endometrial tumors across 1,073 patients were analysed to quantify how mismatch repair-deficient mutational signatures can be integrated into germline variant interpretation.
5 pharma firms trained an AI on 20,167 private protein structures, without sharing one. Accuracy: 35.6% β 52.1%. Analysis: #AIDrugDiscovery #AlphaFold #FederatedLearning #CompBio #OpenFold3 #AISB-1-Fed #MELLODDY
artificialscience.org/2026/09/fede...
Our 2026 LEAD Day scientific panel explores how AI, multi-omics, and increasingly data-rich approaches are changing the way we understand and treat #autoimmune and chronic disease.
#Immunology #Autoimmunity #Health #Medicine #DataScience #CompBio #AI
I'm hiring a bioinformatician! Review of applications starts October 1 with a start date as soon as possible. π§ͺ #Genomics #popGen #CompBio northeastern.wd1.myworkdayjobs.com/careers/job/...
Inversions are balanced structural variants that escape most analyses because of the large repeats that flank them.
New on the BCB CSIC channel: Ian Morilla (IHSM-CSIC-UMA) presents GeoTop, TaelCore, CoMM-BIP and S2-PepAnalyst β four tools worth a look for anyone into computational biology and bioinformatics. π§¬
βΆοΈ youtu.be/JsUQx5fuOCY
Joining our #DataScience Group and working on the @BioFAIR Methods Commons we're seeking a #DevOps Engineer to build, run, and support a cohesive, world-class national service deployed on public cloud.
@fanny-pouyet.bsky.social et al. benchmarked three tree sequence reconstruction methods software by comparing the imbalance of reconstructed trees by these methods with that of the true simulated trees.
S. Kumar, K. Tamura & S. Sharma present a phylogenomic subsampling-upsampling framework (PSU) that cuts runtime/memory by orders of magnitude while preserving accuracy in bootstrap support, model selection, and divergence time estimates.
16/n: This is the culmination of 4 years of my postdoc funded by @wellcometrust.bsky.social and hosted by @mayorlab.bsky.social at @ucl.ac.uk. I also want to thank Jonas Hartmann and @ricardalert.bsky.social for their expertise in #compbio and modelling, which you can read in the paper! β€οΈ
Missense variant effect prediction remains a bottleneck in diagnostic genetics, and current predictors rely on clinical outcomes or population patterns rather than direct measures of functional impact, which creates data circularity.
Not sure who decided I was grown-up enough to be first author on anything, much less a paper, and in @plos.org #CompBio - nevertheless, our paper and toolbox on circular permutation testing for #BrainBody interactions are out now!
π«Άπ» @eliobalestrieri.eurosky.social & @danlikesbrains.bsky.social
We're recruiting for a DevOps Engineering with previous experience deploying and administering web applications or complex multi-user platforms in production environments. π§¬π»