Argh! Obviously #clozapine
@sarahjpharm.bsky.social
@sarahjpharm.bsky.socialArgh! Obviously #clozapine
@psychopharm.bsky.socialNew pharmacovigilance data suggest that #olanzapine and #clozapine may be more strongly associated with pulmonary embolism than other antipsychotics. Whether this reflects medication effects, underlying severe mental illness, or both remains unclear.
đź”— Read more in JCP: www.ovid.com/jnls/psychop...
@psychopharm.bsky.socialFor patients with treatment-resistant #schizophrenia who refuse oral clozapine, intramuscular #clozapine may provide a bridge to treatment. A systematic review found successful transitions to oral therapy were commonly achieved within days.
đź”— Read more in JCP: www.ovid.com/jnls/psychop...
@thementalelf.bsky.socialWould fewer blood tests mean more people get clozapine?
🩸 A UK cohort of 1,025 long-term users switched to 12-weekly monitoring. 🔬 No agranulocytosis over a median of 4 years.
⚠️ But no control group, and a low-risk sample.