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@jamasurgery.comSep 7, 2026, 12:00 PM

Among patients undergoing open rectal resection for #RectalCancer, a powdered #ChondroitinSulfate adhesion barrier system reduced postoperative adhesion incidence, severity, and extent vs no additional procedure.

ja.ma/46eV3Lk

JAMA Surgery RCT: Novel anti-adhesion system significantly reduced adhesions in open rectal resection. 118 adults (mean age 68) with rectal cancer participated. Control group had ~95% adhesions, experimental group (with SI-449) had ~40% (P<.001). Conducted in 53 hospitals in Japan.
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