p53 is crucial for safe reprogramming of somatic cells into pluripotent states, balancing genomic stability with Yamanaka factors to mitigate risks. #CellReprogramming PMID:41999746, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S0092-8674(26)00339-9 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪