Cefepime se asocia con una mayor probabilidad de mortalidad por todas las causas comparado con otros betalactámicos, por lo que debe discutirse la seguridad de cefepime #Cefepime #Mortality jamanetwork.com/journals/jam...
@rcatanho.bsky.social
@rcatanho.bsky.socialCefepime se asocia con una mayor probabilidad de mortalidad por todas las causas comparado con otros betalactámicos, por lo que debe discutirse la seguridad de cefepime #Cefepime #Mortality jamanetwork.com/journals/jam...
@guerreroespejo.bsky.social#Cefepime and mortality: Is cefepime completely safe?
A Bayesian meta-analysis of 110 RCTs (22,608 patients) found a 94.4% posterior probability of higher mortality vs other β-lactams.
An important signal—but not a reason to abandon cefepime.
DOI: 10.1001/jamanetworkopen.2026.33017#IDTwitter
@contagionlive.bsky.social16 years after the #FDA determined that it does not, a new analysis of trials comparing #cefepime with other ß-lactams, including the unpublished industry sponsored trials reviewed by the FDA, disagrees. #IDsky #Medsky
www.contagionlive.com/view/revisit...
@jamanetworkopen.com📊 Meta-analysis: Across randomized clinical trials, #Cefepime was associated with higher odds of all-cause #Mortality vs other β-lactam antibiotics, supporting a nuanced discussion of its role in clinical guidance. ja.ma/465d0fk