🧐Nuclear receptor Rev-erb-α mediates palmitic acid-induced lipid peroxidation in cardiomyocytes
www.sciengine.com/ABBS/doi/10....
#Rev-erb-α
#palmitic acid
#cardiomyocytes
#oxidative stress

🧐Nuclear receptor Rev-erb-α mediates palmitic acid-induced lipid peroxidation in cardiomyocytes
www.sciengine.com/ABBS/doi/10....
#Rev-erb-α
#palmitic acid
#cardiomyocytes
#oxidative stress
Found in translation: Using single-molecule imaging, we show that ERK signaling controls where protein translation happens during hypertrophic stimulation in #cardiomyocytes -revealing a dynamic, localized response. #cardiosky
www.ahajournals.org/doi/10.1161/...
🎓️ EDITOR'S CHOICE🎓️
In this study, Karoline Horgmo Jæger from @simularesearch.bsky.social and colleagues determined properties of human-induced pluripotent stem cell-derived #cardiomyocytes using spatially resolved #electromechanical metrics 🫀 ⚙️
Cardiomyocytes are a key model system for studying heart disease. LAMP1 (yellow, STAR RED), TOM20 (cyan, STAR ORANGE), Myosin (red, STAR GREEN). Imaged at Fraunhofer ITMP Göttingen by Fabian Link. #Cardiomyocytes #STARdyes #abberior #FluorescenceFriday
Reciprocal activation between S100A9 and TLR2 amplifies hypertrophic signaling in mechanically stretched #cardiomyocytes, exacerbating maladaptive remodeling and likely accelerating HF progression, highlighting therapeutic targets. #medsky
To read: doi.org/10.1007/s115...
University of East Anglia (@uniofeastanglia.bsky.social) is hiring:
Senior Research Associate (RA2410)
🫀This new article in Communications Biology shows that #cardiomyocytes derived from tetraploid iPSCs established by cell fusion recapitulate characteristics of post-mitotic cardiomyocytes more precisely than conventional diploid iPSC derived cardiomyocytes. Find more ⬇️
doi.org/10.1038/s420...