@ryanhisner.bsky.social - are there any mutations in these subvariants that you find interesting and that might warrant functional analysis? Thanks!

#BA32

The good news: vaccination boosted neutralizing responses against many currently circulating variants, including the emerging saltation variant PJ.2.1

The less good news: neutralizing antibodies against BA.3.2 showed the weakest boost.

#BA32 #PJ21

New sequences from Saitama and Yamanashi, Japan 🇯🇵, collected from June through September: over 70% are BA.3.2

Looking at September alone, nearly 60% are BA.3.2

As others have noted, the frequency of BA.3.2 in Japan remains unexpectedly high.

#BA32

In Thailand, as in all other countries analyzed, BA.3.2 is most frequently detected in the 0-9 age group. For XFG and other variants (i.e. not XFG*, not NB.1.8.1*), this age group is also the major target but the preference is not as pronounced as that displayed by BA.3.2. #BA32

New sequences from Japan and South Korea, collected from July through September.

BA.3.2 is still circulating at significant levels, accounting for 65% and 28% of sequences, respectively. #BA32

We previously found that #BA32 preferentially infects children aged 0-9 years.

Our analyses focused on Europe, North America, Asia, and Australia, where the median population age is substantially higher than in Africa.

40 new sequences collected in August confirm that BA.3.2 dominance in South Korea has ended.

Less than 10% of the sequences are BA.3.2, XDV subvariants are now dominating. #BA32