Key findings suggest WTC exposure severity was associated with focal reductions bilaterally in the precentral region #AlzResearch

Author contributions: @seanclouston.bsky.social

NEW in A&D: World Trade Center (WTC) neurotoxicant exposure associated with brain atrophy

A study of exposed & unexposed individuals, WTC exposure severity was associated with ⬇️ cortical thickness across most of the cerebral cortex #AlzResearch

alz-journals.onlinelibrary.wiley.com/doi/10.1002/...

Data from the 90+ Study demonstrate multifactorial resilience #AlzResearch

Key findings demonstrate educational level and pulse pressure impact the association of amyloid burden and global cognition.

Learn More: alz-journals.onlinelibrary.wiley.com/doi/10.1002/...

New in A&D: The impact of chronic stress and social support in cognitive decline #AlzResearch

Higher baseline chronic stress ➡️ greater decline in attention in women & greater memory decline in Hispanic vs non-Hispanic participants

Learn more: alz-journals.onlinelibrary.wiley.com/doi/10.1002/...

In a new study, we used structural neuroimaging studies in a cohort of World Trade Center responders. We found that WTC exposure severity was associated with widespread cortical atrophy. Atrophy was worst in those exposed for longest and not wearing masks. #AlzResearch #WTCResearch 🧪

Submit your research to this exciting new section!🧠 #AlzResearch #BSEA

Learn more about the association of age at the time of HRT initiation and Alzheimer’s disease risk! #AlzResearch

How is hormone replacement therapy (HRT) associated with Alzheimer's disease (AD) risk?

Evaluation of postmenopausal women in the UK BioBank demonstrate HRT was associated with lower risk of all-cause dementia and AD #AlzResearch

Full Study: alz-journals.onlinelibrary.wiley.com/doi/10.1002/...

How should clinical studies of the treatment of Alzheimer's disease be interpreted?

Learn more about estimands study outcomes and how to interpret findings with this new review article in A&D! #AlzResearch

Full Article: alz-journals.onlinelibrary.wiley.com/doi/10.1002/...

New in A&D: Prognostic value of plasma %p-tau217 in cognitively unimpaired older adults

Findings suggest that %p-tau217 is a robust prognostic biomarker for AD risk assessment that is comparable with immunoassays #AlzResearch

Learn more: alz-journals.onlinelibrary.wiley.com/doi/10.1002/...

How do social conditions influence brain aging in Latin America?

Compounded social vulnerability is a key determinant of clinical aging and dementia incidence across Latin America #AlzResearch

Learn more: alz-journals.onlinelibrary.wiley.com/doi/10.1002/...