How do pLDDT, ipTM, ipSAE, pDockQ2 and LIS fit together?
See how these metrics work together to assess confidence in an AlphaFold DB complex interface.
🎬 Watch the full tutorial: youtu.be/k4yBqddtPyQ

How do pLDDT, ipTM, ipSAE, pDockQ2 and LIS fit together?
See how these metrics work together to assess confidence in an AlphaFold DB complex interface.
🎬 Watch the full tutorial: youtu.be/k4yBqddtPyQ
A predicted interaction may involve only a small region of a protein complex.
How can we identify confidence in that local interface when the surrounding regions have high PAE?
Our tutorial uses a PAE matrix to explain how LIS can help 👇