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@pdbeurope.bsky.socialSep 24, 2026, 12:12 PM

How do pLDDT, ipTM, ipSAE, pDockQ2 and LIS fit together?

See how these metrics work together to assess confidence in an AlphaFold DB complex interface.

🎬 Watch the full tutorial: youtu.be/k4yBqddtPyQ

#AlphaFold #AlphaFoldDB

@pdbeurope.bsky.socialSep 21, 2026, 2:47 PM

A predicted interaction may involve only a small region of a protein complex.

How can we identify confidence in that local interface when the surrounding regions have high PAE?

Our tutorial uses a PAE matrix to explain how LIS can help 👇

youtu.be/k4yBqddtPyQ

#AlphaFold #AlphaFoldDB

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