Bulk transcriptome of 18 vs 3 mo🐭 cochlear pericyte
Aging➡️
⏫TGFβ signals➡️
⏬IGF-1 & SLC25A33 mito pyrimidine nucleotide transport
IGF-1 microinjection rescues #BloodLabyrinthBarrier ultrastructure & Age-related hearing loss🐭
@haoyin.bsky.social
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@haoyin.bsky.social@haoyin.bsky.socialElamipretide
A mitochondria/cardiolipin-targeting peptide
Aged (8~12 mo)♀️ICR🐭 i.p. Elamipretide for up to 10 days (😮)➡️a transient 1-mo fertility benefit
Metabolomics🐭ovaries
Transcriptomics🐭oocytes
+Evidence on👤oocyte
