Helios is critical for Treg effector differentiation in #adipose #autoimmunity. New study from Angela M. Thornton, Ethan M. Shevach and colleagues @niaidnews.bsky.social:
rupress.org/jem/article/...

Helios is critical for Treg effector differentiation in #adipose #autoimmunity. New study from Angela M. Thornton, Ethan M. Shevach and colleagues @niaidnews.bsky.social:
rupress.org/jem/article/...
TOMORROW โ the main program for the #AdiposeBiology #Conference kicks off in Montreal, Canada! Sable is a proud partner of this event.
Are you joining? If so, we'd love to chat with you, so come say hi!
#Metabolism #Physiology #Adipose #Obesity #Respirometry #IndirectCalorimetry
The Tenth Doctor
Two brilliant events this week but the amazing meetings continue! The abstract deadline for The Matrix: Adipose Remodelled on 7-8 December is on WEDNESDAY! Share the latest research in #adipose tissue biology, bioengineering & extracellular matrix research/biomaterial scaffolds ๐งช bit.ly/Matrix-2026
In @jem.org, Thornton et al. demonstrate that in #Tregs, the transcription factor Helios directly controls Tcf1, Lef1, Id3, and Bach2 to regulate effector Treg generation and terminal differentiation. Mice with Helios-deficient Tregs show #adipose -specific #autoimmunity. rupress.org/jem/article/...
Thornton, Shevach et al. demonstrate that in #Tregs, the transcription factor Helios directly controls Tcf1, Lef1, Id3, and Bach2 to regulate effector Treg generation and terminal differentiation. Mice with Helios-deficient Tregs show #adipose -specific #autoimmunity. rupress.org/jem/article/...
Scientific evidence shows that #bodyweight results from a complex interplay of genetic factors, #diet, & #exercise habits. Throughout adolescence, at least 60 minutes of daily #physicalactivity may be the most effective way to counteract genetic tendencies toward excess #adipose tissue accumulation.
Fourth journal cover by Jake Willows (& second where he was first author of the accompanying paper). Such complexity in #ADIPOSE #CellReportsMethods ๐งช๐งช
Characterization of male #Glyoxalase1 knockout mice demonstrates a role in #lipid #metabolism by the #liver, with minimal effects on #adipose or #kidney function.
doi.org/10.14814/phy...
@physoc.bsky.social
@apspublications.bsky.social
@wileylifesci.bsky.social
The #AdiposeBiology #Conference is just 1 month away (Oct 7โ9, Montreal, Canada) โ we're looking forward to hearing about the latest findings from leading researchers in the field!
#Adipose #Obesity #Diabetes #IndirectCalorimetry #Respirometry #Metabolism #Physiology
Comprehensive Physiology | Review Spotlight ๐ฆ #Adipose Tissue-Derived #Adipokines in #Vascular Physiology and Pathophysiology: Insights and Implications. Read: https://ow.ly/9wQf50ZGFGf
Acute #muscle strain injuries are frequent in #sports. This report shows that #straininjuries led to a rise in fat fraction in the injured muscle in healthy, sports active adults over a 12 month period.
#Adipose #TissueRepair
doi.org/10.14814/phy...