The AACR Special Conference on Pediatric Cancer kicked off with talks from Charles Mullighan and Nicole Michmerhuizen, who discussed how genomics reveals novel biological insights into pediatric leukemia. Learn more on the #AACRBlog: buff.ly/VRibpBw #AACRpediatric26

AACR and Kids Beating Cancer announced a new grant at the AACR Special Conference on Pediatric Cancer that will fund researchers who are studying pediatric leukemia. Read more about this new collaboration and the grant on the #AACRBlog: buff.ly/Kp7EVE4 #AACRpediatric26

Transformative Technologies for Clinical Care:
Brian Compton, Jill Rubinstein, Laura A. T. Kagami, Liya Xu, and Allegra G. Hawkins addressed this topic in a plenary to close out the AACR Conference on Bridging Discovery and Clinical Impact in Pediatric Cancer.
#AACRpediatric26

#AACRpediatric26 cochairs David M. Langenau, Suzanne P. MacFarland, Olivier Delattre, and Annie A. Huang adjourned the AACR Conference on Bridging Discovery and Clinical Impact in Pediatric Cancer. We thank the cochairs, invited speakers, and abstract presenters for their contributions.

Alejandro Gutierrez, Miguel N. Rivera, Olivier Ayrault, Annalena F. Renner, and Troy A. McEachron discussed "Cancer Cell Biology, Organelle Function, and Metabolism" in an #AACRpediatric26 plenary session moderated by Olivier Delattre.

Accelerating Breakthroughs Together:
Joe McDonough, Adam Levy, Kerri Nottage, and Devona Williams explored industry perspectives on collaboration in the pediatric cancer space during a panel discussion at the AACR Conference on Pediatric Cancer. #AACRpediatric26

The Pediatric Cancer article collection highlights the impactful findings that provide insights into fundamental cancer biology that lead to new therapies for a patient population that faces significant barriers to meaningful progress. buff.ly/h5aqZOf #AACRpediatric26

David Malkin, Suzanne P. MacFarland, Olivier Delattre, Emily Boja, Mohamed Bakr, and Esther Rheinbay discussed "Tumor Genomics, Predisposition, and Mosaicism" during a plenary session at the AACR Special Conference on Bridging Discovery and Clinical Impact in Pediatric Cancer.
#AACRpediatric26

Read this Cancer Discovery research article, "CDK8 Inhibition Induces Mediator Trapping and Impairment of the EWSR1::FLI1 Transcriptional Program in Ewing Sarcoma," by David McFadden as a supplement to #AACRpediatric26. buff.ly/useIazj

Advances in Immunotherapy for Pediatric Cancer:
Crystal Mackall, Terry Fry, Andy Huy-Dat Vu, and Kirsten Moziak addressed this topic in a plenary session at the AACR Special Conference on Bridging Discovery and Clinical Impact in Pediatric Cancer. #AACRpediatric26

Read the Pediatric Oncology article series showcasing Clinical Cancer Research articles recommending screening surveillance of childhood cancer predisposition syndromes in an effort to facilitate early detection and treatment of pediatric cancers. buff.ly/9Qeeea4 #AACRpediatric26

Early-career investigators Anand Patel, Caroline Diorio, Peng V. Wu, and Katie A. Greenzang shared their latest research in a special #AACRpediatric26 plenary session organized by the AACR Pediatric Cancer Working Group. @pengvwu.bsky.social

Developmental Pathways in Pediatric Cancer:
Mark Hatley, James Amatruda, Kimberly Stegmaier, Isabelle Janoueix-Lerosey, and Rodney Stewart addressed this topic in a plenary session at the AACR Special Conference on Pediatric Cancer.
#AACRpediatric26 @hatleylab.bsky.social
@amatrudalab.bsky.social

Read this Cancer Discovery research article, "CDK8 Inhibition Releases the Muscle Differentiation Block in Fusion-Driven Alveolar Rhabdomyosarcoma," presented by Kimberly Stegmaier at #AACRpediatric26. buff.ly/6Fl9QqH

John Maris, Annie A. Huang, Sally George, Xueting Xiong, and Thai Hoa Tran discussed "Emerging Mechanisms and Therapeutic Vulnerabilities" in a plenary at the AACR Conference on Bridging Discovery and Clinical Impact in Pediatric Cancer. #AACRpediatric26

Cell States, Plasticity, and Metastatic Progression: David M. Langenau, Jovanna Pavisic, Poul Sorensen, Adam J. Wolpaw, and Noha Shendy addressed this topic in a plenary session at the AACR Special Conference on Pediatric Cancer. #AACRpediatric26

Read the abstracts from the AACR Special Conference in Cancer Research: Bridging Discovery and Clinical Impact in Pediatric Cancer in this supplement to the September 15 issue of Cancer Research: buff.ly/gEo29uj
#AACRpediatric26

Toward a Cure of Acute Leukemia through the Lens of Genomics: Charles Mullighan addressed this topic in a keynote lecture to open the AACR Special Conference on Bridging Discovery and Clinical Impact in Pediatric Cancer. #AACRpediatric26 @cmullighan.bsky.social

Avital Lev, PhD, Senior Editor for Cancer Discovery, is attending #AACRpediatric26 and would love to hear about your research. Connect with her to discuss publishing opportunities in the Journals.

The AACR Special Conference on Bridging Discovery and Clinical Impact in Pediatric Cancer opens this evening in Philadelphia with a keynote lecture by Charles Mullighan.
#AACRpediatric26