🫯Which HSP104 mutation wins in an evolving #Yeast hybrid depends on if SUP35 came from cerevisiae or paradoxus. Scer's weak [PSI+] prion state biases evolutionary outcomes 👉 species-specific alleles reshape selection in hybrid genomes

🧬 #YeastResearch 🧪 #SGD 🔬
www.yeastgenome.org/reference/S1...

🥶 Human eL22 is mutated in cancers but its ribosomal role was unclear. #Yeast work pins down exactly when it acts: an early nucleolar stage of large ribosomal subunit assembly. Without it, cells grow poorly, especially in the cold

🧬 #YeastResearch 🧪 #SGD 🔬
www.yeastgenome.org/reference/S1...

🔍 Meet AMIGa: a newly characterized #Yeast mitochondrial complex required for assembly of both cytochrome c oxidase & ATP synthase. Without it, respiratory intermediates pile up & cells lose respiratory growth 👉 critical coordination role
🧬 #YeastResearch 🧪 #SGD 🔬
www.yeastgenome.org/reference/S1...

🧬 A big thanks to everyone who joined the Munich Yeast Meeting at Helmholtz last week!

🏆 Special thanks to the GfG (German Society of Genetics) for again providing Best Talk and Best Poster prizes. Congrats to the winners!

schmollerlab.com/munich-yeast... @hamperllab.bsky.social

#YeastResearch

🏷️ SUMO E3 ligases are few; their substrates are many. #Yeast study reveals cofactor Esc2 amplifies Nse2's protein-tagging activity at stalled replication forks- targets DNA repair proteins & clears dangerous recombination intermediates
🧬 #YeastResearch 🧪 #SGD 🔬
www.yeastgenome.org/reference/S1...

Study Finds Brettanomyces Spoilage Risk Depends on More Than Presence Alone #WineScience #Brettanomyces #YeastResearch #WineSpoilage #Fermentation

🩺 #Yeast as a disease model: a screen in cardiolipin-deficient yeast identified ebselen as a mitochondrial rescue compound effective across seven fungal models of mitochondrial disease, patient fibroblasts, cardiomyocytes and mice
🧬 #YeastResearch 🧪 #SGD 🔬

www.yeastgenome.org/reference/S1...

📊 Different methods for profiling #Yeast cell walls capture different things. Scatter-based flow cytometry tracks mannan abundance; lectin fluorescence reflects surface composition. Approaches are complementary rather than interchangeable
🧬 #YeastResearch 🧪 #SGD 🔬
www.yeastgenome.org/reference/S1...

🖖 What drives replicative aging in #Yeast? An @oregonstate.edu 🦫 screen found 132 variant genes & 60 differentially expressed genes with little overlap, suggesting longevity is governed by many genes through diverse mechanisms

🧬 #YeastResearch 🧪 #SGD 🔬
www.yeastgenome.org/reference/S1...

✂️ A nonessential #Yeast spliceosome factor w/conserved domain touching the catalytic core turns out to matter more than expected: Cwc15 stabilizes active site & facilitates structural transitions, implications for splice site proofreading
🧬 #YeastResearch 🧪 #SGD 🔬
www.yeastgenome.org/reference/S1...

🧘 #Yeast RPL22 pre-mRNA acts as its own regulator. The intron toggles between 2 competing structures: one blocks splicing, one permits it. Rising Rpl22 levels shift the balance toward inhibition, creating a protein-responsive RNA switch

🧬 #YeastResearch 🧪 #SGD 🔬
www.yeastgenome.org/reference/S1...

♻️ #Yeast Acs2 generates acetyl-CoA locally at chromatin, while its mammalian ortholog ACSS2 also recaptures acetate from histone deacetylation at promoters. This acetate recycling loop couples metabolism ↔️ chromatin state across species
🧬 #YeastResearch 🧪 #SGD 🔬
www.yeastgenome.org/reference/S1...

🏋️ Not all #Yeast strains handle acetic acid equally. Respiratory capacity and carbon flux determine survival under acid stress, and two S. cerevisiae strains show strikingly different responses with implications for strain engineering

🧬 #YeastResearch 🧪 #SGD 🔬

www.yeastgenome.org/reference/S1...

FYI: Researchers in Iran Raise Yeast Biomass to 100.04g/L by Optimizing Culture Conditions #YeastResearch #Biomass #SustainableLab #Fermentation #Microbiology

🧲 How does #Yeast CAF-1 find the replication fork to deposit histones? Via PCNA, using not 1 but 2 PIP motifs. The newly found PIP1β makes atypical extended contacts w/second PCNA subunit; disrupting both motifs abolishes CAF-1 function
🧬 #YeastResearch 🧪 #SGD 🔬

www.yeastgenome.org/reference/S1...

Grateful to receive the @femsjournals.bsky.social Yeast Research Poster Prize at #SMYTE2026 for my work on sterol dynamics at the yeast plasma membrane! Many thanks to Roland and everyone at ICDI for their guidance and support—and to all who stopped by for very cool discussions.
#yeastresearch

🗑️ #Yeast nuclear ubiquitin ligase Uls2 has surprising side job: tagging cytosolic proteins for degradation. Orphaned/ oxidatively damaged proteins aggregate in nucleus & become SUMO-dependent substrate ➡️ = compartment-spanning QC pathway
🧬 #YeastResearch 🧪 #SGD 🔬
www.yeastgenome.org/reference/S1...

🫧 Autophagosome membranes don't just grow by lipid transfer. #Yeast cryo-ET shows vesicles clustering around and fusing with the phagophore rim during expansion, a contribution that was previously attributed only to the nucleation stage

🧬 #YeastResearch 🧪 #SGD 🔬
www.yeastgenome.org/reference/S1...

Great time at #PYFF9 in Valencia! 🧫🍻 Sharing the latest research from #FunGIALab, discussing yeast biology, fermentation and biotechnology, and reconnecting with colleagues made for a fantastic meeting. Excellent science, inspiring discussions, and great people. #YeastResearch #FungalBiotechnology

Researchers in Iran Raise Yeast Biomass to 100.04g/L by Optimizing Culture Conditions #YeastResearch #Biomass #SustainableAgriculture #FoodScience #Biotechnology