Grilled Cheese

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Grilled Cheese is a product of Village Compute

Version devBuilt at: 2026-10-17 20:03:08 EDT

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@csisingapore.bsky.socialOct 16, 2026, 4:14 AM

Last week, CSI Singapore hosted Dr. Anwesha Dey from Genentech. She spoke on the topic “Targeting the PI3K Pathway in Cancers”.

#PI3Kpathway #targetedtherapy #precisionmedicine #molecularoncology #cancerresearch #oncologyresearch #biomedicalresearch

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@sigtrans-sttt.bsky.socialSep 23, 2026, 3:31 PM

Chromosomal instability can drive tumor evolution while creating exploitable dependencies. This review connects the sources and consequences of CIN with tolerance pathways, emerging diagnostics, and therapeutic vulnerabilities.

#STTT #OpenAccess: doi.org/10.1038/s413...

#MolecularOncology

@sigtrans-sttt.bsky.socialSep 23, 2026, 12:30 PM

Cell-cycle dysregulation may provide a therapeutic vulnerability in uterine #Leiomyosarcoma.

This study links CDK/cyclin–phospho-Rb signaling to uLMS and shows antitumor effects of CDK4/6 inhibition with abemaciclib.

#STTT #OpenAccess: doi.org/10.1038/s413...
#CancerBiology #MolecularOncology

Inhibition of CDK/Cyclin-phospho-Rb signaling by amebaciclib may have an antitumor effect against uterine leiomyosarcoma