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@jcb.orgOct 15, 2026, 1:31 PM

#Lipid remodelling enables adaptation to chronic hyperosmotic stress. New study from Thomas D Williams, Christian Klose, Robert Ernst, and Pedro Carvalho @dunnschool.bsky.social: rupress.org/jcb/article/...

#Biochemistry #Membrane #Organelles #Metabolism #LipidDroplets

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@mdpipharma.bsky.socialOct 14, 2026, 9:43 AM

🔬 One amino acid swap transforms Polybia-MP1! HMP1 shows #pH-responsive #membrane reorganization, cholesterol preference & lower cytotoxicity. A promising tool for #targeted #therapeutics & pH-responsive #delivery.

📌 www.mdpi.com/1999-4923/17...
#PeptideDesign #DrugDelivery #pHResponsive

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@kaimurk.bsky.socialOct 12, 2026, 1:51 PM

The final program of the #b42026 blood-brain barrier conference at @ibecbarcelona.eu is out now. Looking forward to giving a talk there about our work on ' #astrocytes actively direct blood-brain barrier integrity via cytoskeleton-assisted #membrane trafficking.'
premc.org/blood-brain-...

@jcb.orgOct 2, 2026, 1:45 PM

Components of an #ESCRT-independent #NuclearEnvelope assembly pathway. New study from Emma M. Sydir, I-Ju Lee, David Pellman @danafarber.bsky.social @harvard.edu and colleagues:
rupress.org/jcb/article/...

#CellCycle #CellDivision #Genetics #Biochemistry #Membrane #lipid

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@biologists.bsky.socialSep 29, 2026, 1:03 PM

@jcellsci.bsky.social are now accepting submissions for their next special issue, which will focus on #membrane dynamics and repair and will be coordinated by Guest Editors Jeremy Carlton and Phyllis Hanson.
Submission deadline: 2 April 2027

Find out more: tinyurl.com/yc2prenb

Call for papers - Special Issue - Membrane Dynamics and Repair
@nigelwatersart.bsky.socialSep 27, 2026, 11:19 PM

Proud to be part of the #Origins exhibition at @aschandbagfactory Kennington London In August 2026 Curated by @monartcurates Monica Mardare with 3 abstract expressionist paintings I'm looking forward 2 being in #shelter & #membrane next shows curated by Monica Mardare @nigelwatersart.bluesky.social

@jcb.orgSep 25, 2026, 4:00 PM

Sydir, Lee, Pellman et al. @harvard.edu @danafarber.bsky.social identify an #ESCRT-independent pathway for #NuclearEnvelope assembly in S. japonicus that involves the conserved proteins, Vid27 and Alx1. rupress.org/jcb/article/...

#CellCycle #CellDivision #Genetics #Biochemistry #Membrane #lipid

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@actacrystd.iucr.orgSep 22, 2026, 1:04 PM

SURFER is a lightweight, GPU-accelerated extension for UCSF ChimeraX that enables rapid semantic differentiation of membrane or membrane-mimic density from macromolecular signal #CryoEM #Segmentation #Membrane doi.org/10.1107/S205...

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@plosbiology.orgSep 17, 2026, 4:30 PM

#Flaviviruses reshape cell membranes to build replication sites, but how are these organized? This study shows that homotypic #membrane tethering driven by host ER protein atlastin-2 is essential for organizing these sites & supporting #viral replication @plosbiology.org 🧪 buff.ly/9MBKCbR

Left: A549 cells expressing HA-tagged ATL2 were infected with ZIKV. After 48 h, cells were fixed with paraformaldehyde and glutaraldehyde, followed by staining for dsRNA and HA using specific antibodies and reversible saponin permeabilization. Cells were imaged by confocal microscopy, then immediately embedded and processed for EM imaging. Right: Model. ATL2 membrane tethering is critical for the spatial organization of flavivirus genome replication. ATL2 tethering dimers bring ER membranes into close contact, facilitating the trafficking of newly synthesized viral genomes from existing vROs into vROs forming on juxtaposed membranes (top). This close connection forms a microdomain which brings together the necessary factors for nascent vRO formation and shields the cytosol-exposed viral RNA from innate immune sensors. Because membrane tethering is reversible, this also permits the expansion of viral genome replication away from sites of existing vRO biogenesis. In the absence of ATL2 membrane tethering (bottom), viral genomes extruded from the vRO are exposed to the cytosol and more likely to form new vROs on the same membrane, leading to the concentration of sites of vRO biogenesis and increased recognition by RIG-I-like receptors (RLRs) in the cytosol.
@jcb.orgSep 16, 2026, 2:31 PM

Dysfunction of #caveolae in muscle disease: a cell biological perspective. From Harriet P. Lo, Robert G. Parton and colleagues (The University of Queensland)
rupress.org/jcb/article/...

#Organelles #Development #Membrane #lipid #Disease #SkeletalMuscle

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@plosbiology.orgSep 16, 2026, 1:05 PM

#Flaviviruses reshape cell membranes to build replication sites, but how are these organized? This study shows that homotypic #membrane tethering driven by host ER protein atlastin-2 is essential for organizing these sites & supporting #viral replication @plosbiology.org 🧪 buff.ly/9MBKCbR

Left: A549 cells expressing HA-tagged ATL2 were infected with ZIKV. After 48 h, cells were fixed with paraformaldehyde and glutaraldehyde, followed by staining for dsRNA and HA using specific antibodies and reversible saponin permeabilization. Cells were imaged by confocal microscopy, then immediately embedded and processed for EM imaging. Right: Model. ATL2 membrane tethering is critical for the spatial organization of flavivirus genome replication. ATL2 tethering dimers bring ER membranes into close contact, facilitating the trafficking of newly synthesized viral genomes from existing vROs into vROs forming on juxtaposed membranes (top). This close connection forms a microdomain which brings together the necessary factors for nascent vRO formation and shields the cytosol-exposed viral RNA from innate immune sensors. Because membrane tethering is reversible, this also permits the expansion of viral genome replication away from sites of existing vRO biogenesis. In the absence of ATL2 membrane tethering (bottom), viral genomes extruded from the vRO are exposed to the cytosol and more likely to form new vROs on the same membrane, leading to the concentration of sites of vRO biogenesis and increased recognition by RIG-I-like receptors (RLRs) in the cytosol.
@plosbiology.orgSep 16, 2026, 8:43 AM

#Flaviviruses reshape cell membranes to build replication sites, but how are these organized? This study shows that homotypic #membrane tethering driven by host ER protein atlastin-2 is essential for organizing these sites & supporting #viral replication @plosbiology.org 🧪 plos.io/3VxdbxK

Left: A549 cells expressing HA-tagged ATL2 were infected with ZIKV. After 48 h, cells were fixed with paraformaldehyde and glutaraldehyde, followed by staining for dsRNA and HA using specific antibodies and reversible saponin permeabilization. Cells were imaged by confocal microscopy, then immediately embedded and processed for EM imaging. Right: Model. ATL2 membrane tethering is critical for the spatial organization of flavivirus genome replication. ATL2 tethering dimers bring ER membranes into close contact, facilitating the trafficking of newly synthesized viral genomes from existing vROs into vROs forming on juxtaposed membranes (top). This close connection forms a microdomain which brings together the necessary factors for nascent vRO formation and shields the cytosol-exposed viral RNA from innate immune sensors. Because membrane tethering is reversible, this also permits the expansion of viral genome replication away from sites of existing vRO biogenesis. In the absence of ATL2 membrane tethering (bottom), viral genomes extruded from the vRO are exposed to the cytosol and more likely to form new vROs on the same membrane, leading to the concentration of sites of vRO biogenesis and increased recognition by RIG-I-like receptors (RLRs) in the cytosol.
@jcb.orgSep 14, 2026, 1:45 PM

Our #Lipid & #Membrane collection highlights work on a novel acyl-CoA binding protein, and lipid organization at the soma–germline boundary in the #Drosophila embryo, and a review on detecting and modulating membrane lipids and a new toolset for #phospholipid monitoring 👉 rupress.org/jcb/collecti...

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@jcb.orgSep 10, 2026, 8:31 PM

Lipid-mediated activation of BLT2 promotes membrane repair to prevent cell death. New study from Yuan Chi, Kazuko Saeki, Takehiko Yokomizo and colleagues (Juntendo University):
rupress.org/jcb/article/...

#Biochemistry #Membrane #lipid

@landfesterdept.bsky.socialSep 10, 2026, 1:48 PM

Gabrielle Anjani Ong presented a talk titled "Disorder in #Polymersomes Membrane Enhances Diffusion of Cargo Molecules", showcasing how #membrane disorder in polymersomes can be leveraged to improve permeability, with exciting implications for drug delivery and nanocarrier design.

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@jcb.orgSep 9, 2026, 3:15 PM

GCL pruning of PIP3 establishes the soma-germline boundary. From Mariyah Saiduddin, Ruth Lehmann @remlehmann.bsky.social and colleagues: rupress.org/jcb/article/...

📕 From our #Lipid and #Membrane collection: rupress.org/jcb/collecti...

#EMBOLipidCode

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@jcb.orgSep 9, 2026, 10:15 AM

PISD acts as a switch between #lipophagy and fatty acid transfer to #mitochondria. From Hanbing Xue, Xingwen Hu, Zhenni Yang, Yan G. Zhao and colleagues: rupress.org/jcb/article/...

📕 From our #Lipid and #Membrane collection: rupress.org/jcb/collecti...

#EMBOLipidCode

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@jcb.orgSep 8, 2026, 8:30 PM

#Ceramide transfer protein regulates G-protein coupled phospholipase signalling in #photoreceptors. New study from Shirish Mishra, Padinjat Raghu @rpadinjat.bsky.social and colleagues @ncbsbangalore.bsky.social:
rupress.org/jcb/article/...

#Neuroscience #Membrane #lipid #Genetics #Drosophila

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@jcb.orgSep 8, 2026, 3:15 PM

#Mitochondria limit coenzyme Q export under #cholesterol biosynthetic stress. From Marjana Ndoci (@mindoci.bsky.social), Thomas Langer, Soni Deshwal (@sonideshwal.bsky.social) et al. rupress.org/jcb/article/...

📕 From our #Lipid and #Membrane collection: rupress.org/jcb/collecti...

#EMBOLipidCode

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@jcb.orgSep 8, 2026, 10:15 AM

Glucose starvation signaling via nucleus-vacuole junction remodeling controls ergosterol synthesis. From Shintaro Fujimoto and Yasushi Tamura (Yamagata University): rupress.org/jcb/article/...

📕 From our #Lipid and #Membrane collection: rupress.org/jcb/collecti...

#EMBOLipidCode

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