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@howweknow.bsky.socialOct 14, 2026, 6:15 PM

A rare genetic correction in a child with inherited immune deficiency helped inspire gene therapy. Alain Fischer explains in Burstcast.

Full discussion: youtu.be/kK-Hg5VYBTo
#GeneTherapy #Immunology #ImmunoSky #Science

@howweknow.bsky.socialOct 13, 2026, 5:43 PM

Your body's antibody factories.

Prof. Rafi Ahmed explains how some plasma cells survive in bone marrow niches and keep producing antibodies.

Full Burstcast: youtu.be/HAZkKVRiqVg

#Science #Immunology #ImmunoSky #Antibodies #ImmuneAging

@castltrastondrs.medsky.networkOct 13, 2026, 6:34 AM

#Medsky🧪 #immunosky @science.org Blamed it on the genes ! And how XX and XY chromosomes influence aging and diseases, including neurological, immune, cancer, and cardiometabolic disorders.

www.science.org/doi/10.1126/...

@apcmicrobiomeirel.bsky.socialOct 12, 2026, 10:33 AM

Gut microbes turn peanuts into metabolites linked with immune signalling.

New APC-led research in 𝐆𝐮𝐭 𝐌𝐢𝐜𝐫𝐨𝐛𝐞𝐬 from Emer Shannon, @jenswalter15.bsky.social, Liam O'Mahony & colleagues.

Paper: buff.ly/f73NcmU
News: buff.ly/OqUaSM0

#Microbiome #FoodAllergy #Immunosky

@tandfresearch.bsky.social

Research announcement: Gut microbes convert peanut components into immunoregulatory metabolites — infographic shows stepwise flow (peanut components → gut microbes → immunoregulatory metabolites → immune signalling), UCC logo, Shannon et al., 2026.Graphic summarizing a study that analyzed fecal samples from 343 twelve‑month‑old children, compared gut microbiome features linked to peanut consumption, and used human gut fermentation models to test microbial breakdown of peanuts.Peanut fermentation altered microbial metabolism: 188 metabolites significantly changed, short-chain fatty acid production increased, and Bifidobacterium longum subsp. longum strain 160 produced indole-3-lactic acid.Infographic summarizing a study linking early diet (peanuts) → gut microbes → microbial metabolites → immune signalling, with three takeaways: clearer peanut microbial metabolism, metabolites tied to immune regulation, and a stronger basis for studying early life diet–microbiome interactions.
@castltrastondrs.medsky.networkOct 10, 2026, 6:07 AM

#Medsky🧪 #immunosky #IDsky #publichealth understanding #mucosalimmunity & #mucosalvaccines in vaccine development

@castltrastondrs.medsky.networkOct 10, 2026, 5:46 AM

#Medsky🧪 #immunosky #oncosky #Lymphocyteactivationgene3 (LAG3) protein is a key immune inhibitory checkpoint receptor that suppresses #Tcell activation, proliferation and effector functions to maintain immune homeostasis and tolerance. In persistent pathological settings,

@braithwaiteat.bsky.socialOct 9, 2026, 2:55 PM

​Which in vitro model best reflects human disease? We compared scRNA-seq profiles of >150K PBMCs across 11 stimuli, mapping them against inflammatory diseases like SLE to highlight the most clinically relevant models. Free data: doi.org/10.1186/s130... 🧪🧬🖥️ #immunosky #scRNAseq #SingleCell

A multi-panel figure summarizing the experimental workflow and single-cell RNA sequencing results for in vitro stimulated immune cells. The top left panel illustrates the experimental workflow, showing healthy donor PBMCs treated with immunomodulators for 48 hours, followed by cell fixation, SPLiT-Seq single-cell barcoding, RNA sequencing, and downstream comparative analysis. The bottom left panel displays a UMAP plot showing the distinct clustering of various immune cell types across myeloid and lymphoid lineages, including monocytes, B cells, T cells, and NK cells. The right panel features a grid plot comparing the responses of these specific immune cell types across 11 different stimulations. This plot highlights the mean fold change (represented by color) and the number of differentially expressed genes (represented by the size of the squares) per cell type and stimulation condition.
@mitchmd.bsky.socialOct 9, 2026, 1:09 PM

I'm pleased to announce the latest work from the Grayson Lab. Check out the disparate nature of atopy versus NRG1 in protection from lethal respiratory viral infections. This is work funded by #NIH. #Immunosky #Immunology #Medsky #virus #scRNAseq

www.nature.com/articles/s41...

@tuurekinnunen.bsky.socialOct 9, 2026, 6:29 AM

New research out @eurjimmunol.bsky.social: onlinelibrary.wiley.com/doi/10.1002/...

What does the immune landscape inside an inflamed joint look like in patients with juvenile idiopathic arthritis (JIA)?

We profiled synovial fluid using single-cell multiomics + flow cytometry. 👇 #immunosky 🧵 1/7

@inflames-flagship.bsky.socialOct 8, 2026, 12:38 PM

Exciting week ahead of us, we happy to welcome our Visiting Professor Mark Ansel to Turku, Finland! #ImmunoSky #MedSky #science

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@castltrastondrs.medsky.networkOct 8, 2026, 4:07 AM

#Medsky🧪 #IDsky #immunosky #vaccinesmatter #publichealth XFG-adapted mRNA vaccination significantly ⏫️ neutralising activity against all tested #SARSCoV2 variants, boosting cross-reactive humoral immunity across multiple lineages.According to early immunogenicity data
www.medrxiv.org/content/10.6...

@castltrastondrs.medsky.networkOct 2, 2026, 5:49 AM

#Medsky🧪 #Microsky #immunosky #publichealth The autoimmune regulator (Aire) promotes #Tcell tolerance through promiscuous #geneexpression in medullary thymic epithelial cells, but growing evidence points to additional roles beyond thymic tolerance
@cellpress.bsky.social
www.cell.com/immunity/ful...

@follicular.bsky.socialOct 1, 2026, 5:38 PM

More evidence worms are good for you! 😂 Very cool study.
#Immunosky
www.nature.com/articles/s41...

@lydiabeckeriii.bsky.socialOct 1, 2026, 8:03 AM

At 12 PM today, the @britsocimm.bsky.social Manchester Immunology Group Seminar takes place in the Smith Lecture Theatre.

Dr Julie Ribot from the Gulbenkian Institute for Molecular Medicine presents her work on immune system-brain interaction: “γδ17 T cells in neuro-immune cross-talks”. #ImmunoSky

At 12 PM Oct 1, the BSI Manchester Immunology Group Seminar takes place in the Smith Lecture Theatre. Dr Julie Ribot from the Gulbenkian Institute for Molecular Medicine presents her work on immune system-brain interaction: “γδ17 T cells in neuro-immune cross-talks”.
@fanofactor.bsky.socialSep 28, 2026, 8:00 AM

🚨 Immcantation users, don't forget to submit your 250-word abstract by October 1st!

👉 Find the template, submission instructions, and registration form here: immcantation.github.io/users-meetin...

#immunosky

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@jennyrohn.bsky.socialSep 28, 2026, 6:55 AM

"P. aeruginosa subverts mucosal immunity and establishes a self-sustaining immunopathological loop, offering potential targets for #CF precision therapies."

really interesting - may have analogies in other infections too

#MicroSky #ImmunoSky #IDSky

@microbesinfect.bsky.socialSep 24, 2026, 6:44 PM

A commensal-derived sugar protects against #obesity by regulating immunometabolism.

Clostridium immunis sugar lowers IL‑22 to boost visceral fat burning and counter obesity.

www.sciencedirect.com/science/arti... #microbiota #immunity #metabolism #MicroSky #ImmunoSky #MedSky

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@airr-community.bsky.socialSep 22, 2026, 3:10 PM

Don't forget to register for the upcoming AIRR-C Seminar Series on September 24th!

#immunosky

@apcmicrobiomeirel.bsky.socialSep 22, 2026, 9:01 AM

A new paper in 𝐏𝐞𝐝𝐢𝐚𝐭𝐫𝐢𝐜 𝐀𝐥𝐥𝐞𝐫𝐠𝐲 𝐚𝐧𝐝 𝐈𝐦𝐦𝐮𝐧𝐨𝐥𝐨𝐠𝐲: FLORAL 2025 vs CORAL 2020. Antibiotic exposure: 13.1% vs 6.2%; peanut introduction: 44% vs 13.6%.

Paper: buff.ly/ku4RwtC
More: buff.ly/Vk9yGys
#Microbiome #Allergy #immunosky

@wiley.com @wileyhealth.bsky.social @rcsi.bsky.social

Study announcement comparing early-life exposures in infants born during COVID-19 (CORAL 2020) vs post‑pandemic (FLORAL 2025), noting by 6 months antibiotic exposure was about twice as common and peanut introduction over three times more common in FLORAL, with higher hospitalisation rates.
@biomedj.bsky.socialSep 22, 2026, 7:07 AM

The Mononuclear Phagocyte System: A Dispersed Organ.

Mononuclear phagocytes show broad organ roles and plasticity. This issue reviews their systemic functions beyond #immunity

www.sciencedirect.com/science/arti... #OpenAccess #immunology #ImmunoSky #MedSky

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