Interesting talk by Julius Pampel from the group of Kevan Shokat at #ICBS2026.
He talked about his work on targeting K-Ras Q61 mutants with #CovalentInhibitors.
@stephanhacker2.bsky.social
@stephanhacker2.bsky.socialInteresting talk by Julius Pampel from the group of Kevan Shokat at #ICBS2026.
He talked about his work on targeting K-Ras Q61 mutants with #CovalentInhibitors.
@stephanhacker2.bsky.socialExciting talk by Yoav Shamir from the group of Nir London at #CovModDrugDisvov!
He talked about cofolding in Alphafold3 to identify #CovalentInhibitors with novel structures for BTK.
#DrugDiscovery #Kinase #ChemSky #ChemBio #Science
@britpharmsoc.bsky.social
@stephanhacker2.bsky.socialInteresting talk by Chloe Oxford from GSK at #CovModDrugDiscov.
She talked about a MALDI-TOF-MS-based assay to characterize the binding of #CovalentInhibitors to challenging proteins with resolution of the binding site.
@stephanhacker2.bsky.socialInteresting talk by @ljwalport.bsky.social at #CovModDrugDiscov.
She talked about the discovery of potent peptide-based #CovalentInhibitors using mRNA display.
www.nature.com/articles/s42...
#mRNA #RNA #DrugDiscovery #ChemBio #ChemSky #Science
@britpharmsoc.bsky.social
@stephanhacker2.bsky.socialInteresting talk by Madeeha Ali at #CovModDrugDiscov.
She talked about her exciting work on studying the kinetics of #CovalentInhibitors.
@stephanhacker2.bsky.socialGreat talk by David Heppner (@heppnerd.bsky.social) at #CovModDrugDiscov.
He gave exciting insights into rigorously characterizing #CovalentInhibitors using crystal structures and kinetics.
@stephanhacker2.bsky.socialInteresting talk by Jonathan Pettinger from GSK at #CovModDrugDiscov.
He talked about the power of direct-to-biology (D2B) approaches for fast SAR studies of #CovalentInhibitors.
#D2B #DirectToBiology #DrugDiscovery #ChemBio #ChemSky #Science
