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@prepub-singlecell.bsky.socialSep 11, 2026, 7:01 AM

A single-nucleus and spatial transcriptomic atlas of the Syrian hamster preoptic area across hibernation states #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.09.04.749515v1

@prepub-singlecell.bsky.socialSep 11, 2026, 4:01 AM

SpCAST enables scalable and interpretable integration of single-cell RNA sequencing and single-cell-resolved spatial transcriptomics #SingleCell 🧪🧬🖥️
https://arxiv.org/abs/2605.26904

@prepub-singlecell.bsky.socialSep 11, 2026, 4:01 AM

Human genetic risk for major depressive disorder implicates motor cortex PVALB⁺ inhibitory neurons #SingleCell 🧪🧬🖥️
https://www.medrxiv.org/content/10.64898/2026.09.08.26362568v1

@prepub-singlecell.bsky.socialSep 11, 2026, 4:01 AM

Rapid thermal adaptation in coral photosymbionts draws on standing variation and recombination #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.09.08.749829v1

@prepub-singlecell.bsky.socialSep 11, 2026, 4:00 AM

Unification of Signal Transform Theory #SingleCell 🧪🧬🖥️
https://arxiv.org/abs/2605.11589

@prepub-singlecell.bsky.socialSep 11, 2026, 4:00 AM

Domain Elastic Transform: Bayesian Function Registration for High-Dimensional Scientific Data #SingleCell 🧪🧬🖥️
https://arxiv.org/abs/2603.21235

@prepub-singlecell.bsky.socialSep 11, 2026, 4:00 AM

scDEFT: A deep learning framework for drug-effect prediction and counterfactual reasoning #SingleCell 🧪🧬🖥️
https://arxiv.org/abs/2609.10831

@prepub-singlecell.bsky.socialSep 11, 2026, 4:00 AM

A comparative single-cell transcriptomic atlas for diverse populations of vertebrate hair cells #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.09.02.748811v1

@prepub-singlecell.bsky.socialSep 11, 2026, 4:00 AM

Reference-guided pseudotime inference across species and biological contexts #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.09.04.749461v1

@prepub-singlecell.bsky.socialSep 11, 2026, 1:00 AM

A spatial single-cell transcriptomic atlas of metastatic breast cancer progression #SingleCell 🧪🧬🖥️
https://www.medrxiv.org/content/10.64898/2026.09.04.26361940v1

@prepub-singlecell.bsky.socialSep 11, 2026, 1:00 AM

A Single-cell Spatiotemporal Atlas Encoding Age-dependent Evolution of the Ischemic Penumbra #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.09.08.750251v1

@prepub-singlecell.bsky.socialSep 10, 2026, 10:02 PM

PHAROS: turning single-cell perturbation models into target-directed drug-combination screens #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.09.08.749477v1

@prepub-singlecell.bsky.socialSep 10, 2026, 10:01 PM

iPSC-Derived Chondroprogenitors as a Promising Cell Source for Cartilage Engineering: A Comparison with MSCs in Unmodified and Peptide-Functionalized Alginate Hydrogels #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.09.08.750074v1

@prepub-singlecell.bsky.socialSep 10, 2026, 10:01 PM

Transcriptomic Characterization of Terminal Complement Complex-bound Cells in Human Choroid Using Single-Cell RNA Sequencing #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.09.05.749603v1

@prepub-singlecell.bsky.socialSep 10, 2026, 10:01 PM

TGF-β- and IL-1-dependent fibroblast states differentially shape pancreatic cancer microenvironments and metastasis #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.09.08.750042v1

@prepub-singlecell.bsky.socialSep 10, 2026, 10:01 PM

Highly resolved tumor architecture via matched spatial and nucleus transcriptomics from a single tissue section #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.09.07.749790v1

@prepub-singlecell.bsky.socialSep 10, 2026, 7:01 PM

Discovery of compounds targeting human acute myeloid leukemia stem cells via a novel high-throughput screen #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.09.09.750169v1

@prepub-singlecell.bsky.socialSep 10, 2026, 7:01 PM

A Distal Super-Enhancer Regulate CD47 Expression and Promotes Macrophage-Mediated Phagocytosis of Ovarian Cancer Cells #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.09.07.749763v1

@prepub-singlecell.bsky.socialSep 10, 2026, 7:01 PM

A Full Spectrum Fibroblast Profiling Panel Reveals Phenotypic and Metabolic Heterogeneity of Cancer-Associated Fibroblasts at the Single-Cell Level #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.09.07.749987v1

@prepub-singlecell.bsky.socialSep 10, 2026, 7:00 PM

An in vitro System for Studying Osteochondrogenic Differentiation of Smooth Muscle Cells and Modeling Intimal Vascular Calcification #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.09.05.749615v1