explore | Grilled Cheese

Universal seropositivity, markers of recurrent reactivation, and a convergent T-cell response implicate cytomegalovirus in Susac syndrome #SingleCell 🧪🧬🖥️
https://www.researchsquare.com/article/rs-11006811/latest

Spatial Multi-Omics Reveals an Immunometabolic Niche Defined by PROM1+SLC27A4+ Tumor-Initiating Cells and CD8A+ABCA12+ Exhausted T Cells in HER2-Positive Breast Cancer #SingleCell 🧪🧬🖥️
https://www.researchsquare.com/article/rs-10887996/latest

Integrated Multi-Omics Analysis Reveals the Neuroprotective Mechanism of the Inflammation Repressor TNIP1/ABIN1 in Microglia following Ischemic Stroke #SingleCell 🧪🧬🖥️
https://www.researchsquare.com/article/rs-10563729/latest

Insulators As Dynamic, Tunable Regulators of Enhancer-Promoter Coordination in Living Drosophila Embryos #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.09.09.750400v1

Mapping Uterine Remodeling from Pregnancy to a New Homeostatic State #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.09.07.749876v1

AP-1 specifies developmental versus fibrotic extracellular matrix transcriptional programs in the lung #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.09.10.750752v1

ImmuneLens: linking transcriptional states and TCR clonotypes through disentangled multimodal learning #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.09.08.749998v1

Longitudinal single-cell and spatial transcriptomics reveals intratumor heterogeneity, therapeutic response, and comparative value of canine marginal zone lymphoma #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.09.10.750253v1

Led by the Earlham Institute in Norwich, with @samsocean.bsky.social, the Culture Collection of Algae and Protozoa, and @aau.dk, the project brings together international expertise in #protist culturing, #singlecell genomics, and #longread sequencing. 🧬🦠🔬

Adenosine impairs T cell function via activation of purine salvage pathway and AMP-induced inhibition of pyrimidine nucleotide biosynthesis #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.09.07.749884v1

Integrative Genetic and Single-Cell Analysis Reveals Macrophages as Key Mediators Linking Aging and Osteoporosis #SingleCell 🧪🧬🖥️
https://www.medrxiv.org/content/10.64898/2026.09.09.26362574v1

The Separable Organization of Immune Transcriptional Responses #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.09.09.750474v1

Lifelong Invertebrate Chordate Central Nervous System Regeneration is Driven by a Migrating Pool of Conserved Neural Stem Cells Program #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.09.11.750342v1

A single-cell view of human tissue aging reveals architectural decline beyond cellular composition #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.09.06.749715v1

A transitional senescence program drives inflammatory monocyte state expansion in aging humans #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.09.09.750459v1

Agentic-AI-ready genome-wide poxvirus-host interaction screen refined by a protein language model #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.09.10.750412v1

Transient morphogenetic constraints organize self-assembling axon neighborhoods for robust yet flexible wiring #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.09.09.750528v1

An immunophenotype-coupled transcriptomic atlas of mouse hematopoietic progenitors #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.09.08.750044v1

Soluble pathogenic tau transmission to astrocytes drives acute oxidative damage, cellular senescence, and neurovascular uncoupling in a model of Alzheimers tauopathy #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.09.08.750215v1