(A Chem) Sub-20 μm Non-Matrix-Matched U−Pb Dating by LA-Q-ICP-MS Using Pre-Cell Water-Vapor-Assisted Laser Ablation and Quadratic Polynomial Regression Intercept Correction: AbstractAccessory-mineral U−Pb geochronology by laser ablation quadrupole inductively coupled plasma mass… #MassSpecRSS

(A Chem) Laser-Induced Graphene Microarrays for Enhanced Quantitative Precision in Surface-Assisted Laser Desorption/Ionization Mass Spectrometry: AbstractLaser desorption/ionization mass spectrometry offers distinct advantages for biomolecular analysis owing to its high salt… #MassSpecRSS

(A Chem) Integrating Ion Mobility Mass Spectrometry Data with AlphaFold and Rosetta Improves Protein Complex Structure Prediction: AbstractIon mobility mass spectrometry (IM-MS) provides valuable structural information about protein shape and size through collision cross section (CCS).… #MassSpecRSS

(BioRxiv All) mzQC: a versatile way to communicate quality information for biological mass spectrometry: Reliable quality control (QC) is essential for reproducible biological mass spectrometry, yet QC information is still typically stored in tool-specific, poorly… #BioRxiv #MassSpecRSS

(J Phys Chem A) An Experimental
and Computational Investigation of
the Kinetics of Branched Butyl Radicals 2-Methylpropan-1-yl
and 2-Methylpropan-2-yl with Molecular Oxygen: AbstractWe have measured
the rate coefficient for the reaction
between
the 2-methylpropan-1-yl radical and… #MassSpecRSS

(JACS) Aziridination-Based
Crosslinking Enables Site-Resolved
Elucidation of Lipid Binding and Protein Conformational Changes: AbstractLipid–protein interactions play critical roles
in cellular
function, yet their site-resolved characterization remains challenging
due to the dynamic… #MassSpecRSS

(JACS) Isobaric Intramolecular
Paternò–Büchi
Reactions Enable Multiplexed Quantitation of Fatty Acids down to C═C
Locations: AbstractFatty acids (FAs), as key lipids in energy storage and
signaling,
are dynamically regulated to maintain cellular homeostasis. FA profiling
has become a… #MassSpecRSS

(JACS) METTL3–METTL14
Heterodimer Assembly Enables
Multivalent RNA Engagement and Is Tuned by Interface-Targeting Peptides: AbstractRNA N6-methyladenosine (m6A) deposition by
the METTL3–METTL14 complex regulates RNA metabolism and thereby
influences cell differentiation and stress… #MassSpecRSS

(JASMS) Mechanistic Studies
of the Gas-Phase Cornforth Rearrangement
Using Collision-Induced Dissociation and Density Functional Theory: AbstractA mechanistic investigation of the gas-phase Cornforth
rearrangement
of protonated 2,4,5-trisubstituted oxazoles is presented. Upon… (RSS) #MassSpecRSS

(JASMS) Fast Sex Wellness
Products Screening Using a Portable/Field
Deployable MS Equipped with a Direct Sampling Atmospheric Pressure
(DSAP) Source: AbstractSex-wellness
products, including herbal formulations, API-containing
tablets, creams, and sprays, are widely used to… (RSS) #MassSpecRSS

(JASMS) Gas Phase Structures of Cationized Imidacloprid and
Cationized Chlorpyrifos: AbstractNeonicotinoids and
organophosphates are important analytes due
to their use as insecticides and environmental profiles. Cationized
imidacloprid and chlorpyrifos as prototypical examples… (RSS) #MassSpecRSS

(JASMS) Evaluating the Effect
of Chromatographic Chelator
Modifiers on Metabolite Levels in Untargeted Liquid Chromatography–Mass
Spectrometry: AbstractMetal-sensitive
metabolites frequently exhibit poor chromatographic
performance during liquid chromatography–mass spectrometry… (RSS) #MassSpecRSS

(ACA) Corrigendum to “Resolving drug uptake heterogeneity in 3D organ on chip models via live single-cell microsampling and ion mobility mass spectrometry” [Anal. Chem. Acta, 1422, (2026), 346065]: Publication date: 8 December 2026

Source: Analytica Chimica Acta, Volume… #AChimActa #MassSpecRSS

(J Proteom) Integrated analysis identifies dysregulated secretory proteins and crotonylation profiles associated with immune regulation in IgA nephropathy: Publication date: Available online 7 October 2026

Source: Journal of Proteomics

Author(s): Jiamin Chen, Wei Zhang, Yong Dai,… #MassSpecRSS

(J Sep Sci) Heart‑Cutting Two‑Dimensional Liquid Chromatography/High‑Resolution Mass Spectrometry and Complementary High‐Performance Liquid Chromatography Methods for Comprehensive Impurity Profiling and Quality Control of Dalbavancin Hydrochloride: A heart-cutting… #JSepSci #MassSpecRSS

(JPR) How to Design
1000-Plex Mass Tags Using the Differential
Mass Defect: AbstractMultiplexing samples in mass-spectrometry-based proteomics
has
long been accomplished by isotopologues of small molecules. These
chemically identical ″mass tags″ conjugate to peptides
to encode samples… #MassSpecRSS

(A Chem) Efficient Separation of Disaccharide Isomers Using Ion Mobility Spectrometry by Metal Cation and Anion Assisted Strategy: AbstractThe rapid separation and identification of disaccharide isomers pose a significant analytical challenge in fields such as food science and… #MassSpecRSS

(A Chem) LC−MS-Based Chlorine-Signature Query Engine Strategy for Automated Discovery of Phosphate-Containing Metabolites: AbstractComprehensive profiling of phosphate-containing compounds (PCCs) in untargeted metabolomics remains challenging due to their high hydrophilicity, poor… #MassSpecRSS

(A Chem) IMSS: An Integrated Mass Spectrometry Strategy for Targeted Discovery of Cyclopeptides  Exemplified by Phakellicyclins from the Marine Sponge Phakellia fusca: AbstractCyclopeptides (CPs) represent a structurally diverse class of bioactive natural products but remain… #MassSpecRSS

(J Chrom A) Offline two-dimensional liquid chromatography-electrochemical detection combined with liquid chromatography-high resolution mass spectrometry for comprehensive characterization and antioxidant activity evaluation of Ilex asprella leaves: Publication date: 8 November… #JChrom #MassSpecRSS