Intramembrane proteolysis: principles of substrate recognition and membrane protein fate pubmed.ncbi.nlm.nih.gov/42833984/ #cryoEM

PowerFit: An updated framework for fast rigid-body fitting into cryo-EM density maps. www.biorxiv.org/content/10.64898/2026.09.29.755289v1 #cryoEM

Although #cryoEM structures of the seeded aggregates remain to be confirmed, STED microscopy reveals that different seeds lead to distinct morphologies of the seeded aggregates inside the cultures, which will be interesting for our future studies on the distinct downstream effects of tau strains.

The #cryoEM structure of the induced tau filaments reveals that the structure of the seeds in replicated faithfully in this experimental system.

Mycothiazole enables structural characterization of entire ubiquinone-accessing tunnel in mitochondrial respiratory complex I www.biorxiv.org/content/10.64898/2026.10.01.756109v1 #cryoEM

Long-form hibernation-promoting factor coordinates 100S assembly and translational repression www.biorxiv.org/content/10.64898/2026.10.02.756224v1 #cryoEM

We're highlighting this recent publication from @feinberg.northwestern.edu using #cryoEM to show how temperature and intracellular Ca²⁺ reshape the pharmacology of TRPM4. Notably, this cryoEM work was done entirely with 200kV Glacios Cryo-TEM. Paper: ter.li/86gu1evw

A Multi-Scale Computational Framework for Anti-Persister Tuberculosis Drug Discovery pubmed.ncbi.nlm.nih.gov/42827386/ #cryoEM

Decoding full-length factor VIII through the structural and functional lens of its B domain pubmed.ncbi.nlm.nih.gov/42827696/ #cryoEM

Cryogenic Scanning Electron Nanobeam Diffraction Workflows for Structural Characterization of Beam-Sensitive Battery Interfaces pubmed.ncbi.nlm.nih.gov/42825512/ #cryoEM

The CUP pilus SMF-1 utilizes a specific antiparallel bundling mechanism to initiate biofilm formation pubmed.ncbi.nlm.nih.gov/42826101/ #cryoEM

Structural and kinetic mechanisms of state-dependent potassium channel inhibition pubmed.ncbi.nlm.nih.gov/42826183/ #cryoEM

Transposon end recognition and pairing by I-F3 CRISPR-associated transposase pubmed.ncbi.nlm.nih.gov/42826193/ #cryoEM

Reanalysis of a published cryo-EM dataset reveals domain-level variability in the Hrd1-Hrd3 complex pubmed.ncbi.nlm.nih.gov/42826650/ #cryoEM

Structural heterogeneity of CTE Type I tau filaments with an interface-shifted polymorph pubmed.ncbi.nlm.nih.gov/42826653/ #cryoEM

Serum IgM crosslinks hepatitis B subviral particles into supramolecular immune complexes www.biorxiv.org/content/10.64898/2026.09.30.755772v1 #cryoEM

Here you can see a cryoEM structure of CbCash filament from Cloroflexi bacterium in complex with tRNA (PDB code: 9YLU)

Rendering by Francisco J. Enguita made with #ProteinImager

#SciArt #molecularart #cloroflexi #filament #cbcash #tRNA #cryoem

Structural streamlining of axonemal doublet microtubules in Plasmodium male gametes www.biorxiv.org/content/10.64898/2026.10.01.755548v1 #cryoEM

Taccalonolide AJ uncouples tubulin GTP hydrolysis from microtubule depolymerization www.biorxiv.org/content/10.64898/2026.09.30.755716v1 #cryoEM

Sequential assembly in vivo of the bacteriophage P22 genome translocation channel pubmed.ncbi.nlm.nih.gov/42818598/ #cryoEM