Humans evaluate info by relative evidence, not absolute uncertainty. AI models predict behavior. Fascinating insights! 🌟 PMID:42362882, Nat Neurosci 2026, @NatureNeuro https://doi.org/10.1038/s41593-026-02342-9 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪

A novel in vivo gene switch responsive to electromagnetic fields (EMFs) allows precise spatiotemporal gene expression control. Key findings reveal Cyb5b as an essential EMF sensor. PMID:41985457, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S0092-8674(26)00330-2 #Medsky #Pharmsky #RNA #ASHG 🧪

Revolutionary study shows LEAPER 2.0 enabled long-term DMD reversal in monkeys & humans via circ-arRNA-guided exon skipping, spurring hope for treatment! #DuchenneMuscularDystrophy PMID:42269605, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S0092-8674(26)00589-1 #Medsky #Pharmsky #RNA #ASHG 🧪

A new CRISPR knockout mouse library (84 lines) enables in vivo screening of host factors in influenza A research, bridging gaps in translation from in vitro studies. PMID:42302780, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S009286742600591X #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪

A recent Cell study reveals autoantibodies in 25% of long COVID patients drive symptoms like pain, fatigue, & neurocognitive issues, highlighting disease complexity. PMID:42208496, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S0092-8674(26)00511-8 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪

New insights reveal MAP1B, a microtubule-associated protein, shuttles to the nucleus in neural stem cells, linking cytoskeletal dynamics to cell fate and disease. PMID:42276043, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S0092-8674(26)00578-7 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪

Research reveals that METHYLENE BLUE SENSITIVITY1 (MBS1), a zinc-finger protein, helps chloroplasts sense singlet oxygen (¹O₂) to boost photoprotection in high light. PMID:42309053, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S0092-8674(26)00642-2 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪

New study reveals excessive vascular integrity in small-cell lung cancer creates an immune desert. "Reverse normalization" may boost immunotherapy efficacy—time to rethink strategies! PMID:42349379, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S0092-8674(26)00634-3 #Medsky #Pharmsky #RNA 🧪

New study reveals mesenchymal drift as a unifying mechanism linking key aging hallmarks, showing how cells lose identity and adopt mesenchymal traits, fostering decline. PMID:42208498, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S0092-8674(26)00455-1 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪

Mammalian cortical connectomes show complex, region-specific connectivity. A new model reveals how physical constraints shape this intricate 3D network, uncovering mysteries of brain architecture. PMID:42361798, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S0092-8674(26)00648-3 #Medsky #RNA 🧪

Discovery of Galvanin (TMEM154) reveals its critical role in electric-field-guided cell migration, shedding light on how 40% of immune cells navigate to wounds. PMID:42127892, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S0092-8674(26)00461-7 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪

Kongming defense uses a helical KomBC complex activated by dITP during phage attack. Structural analysis reveals KomB & KomC's role in antiviral action. 🧬🔍 PMID:42362564, Nat Commun 2026, @NatureComms https://doi.org/10.1038/s41467-026-74710-9 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪

Mapped the olfactory system in mice using MERFISH, revealing distinct expression patterns of 100+ olfactory receptors vital for social odor detection and processing. PMID:42054995, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S0092-8674(26)00389-2 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪

D-SPIN constructs gene regulatory networks from scRNA-seq data, revealing how cells respond to perturbations, maintain homeostasis, and transition states. Exciting insights into cellular control! PMID:42127893, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S0092-8674(26)00463-0 #Medsky #RNA 🧪

New study reveals that cancer metastasis is influenced by specific microenvironments, showing 5 key niche traits like macrophage enrichment & T cell depletion. #CancerResearch PMID:42054994, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S0092-8674(26)00398-3 #Medsky #Pharmsky #RNA #ASHG 🧪

CRISPR-Cas13a and HicAB synergy limits phages in E. coli, revealing bacterial defense… PMID:42362581, Nat Commun 2026, @NatureComms @OTSociety @NAR_Open https://doi.org/10.1038/s41467-026-74930-z #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪

Scientists find S. cerevisiae can help reduce vulvovaginal candidiasis severity by modulating fungal virulence and immune response, impacting millions globally. PMID:42362572, Nat Commun 2026, @NatureComms https://doi.org/10.1038/s41467-026-74733-2 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪

New research reveals two clades of SARS-CoV-2-related coronaviruses in Thai horseshoe bats. One clade binds human ACE2, raising concerns for potential zoonotic spillover. PMID:42097139, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S009286742600454X #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪

Stroke impacts 15M annually; 5M are left disabled. New randomized trial uses VR and neurostimulation for recovery. 🧠✨ PMID:42362865, Nat Med 2026, @NatureMedicine https://doi.org/10.1038/s41591-026-04486-4 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪

Developed D&D-seq for single-cell mapping of regulatory DNA-protein interactions, revealing insights on TF binding dynamics, chromatin accessibility, and gene expression! PMID:42242226, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S0092-8674(26)00573-8 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪