Transcriptomic Models for Immunotherapy Response Prediction Show Limited Cross-cohort Generalisability #SingleCell 🧪🧬🖥️
https://arxiv.org/abs/2604.05478

Domain Elastic Transform: Bayesian Function Registration for High-Dimensional Scientific Data #SingleCell 🧪🧬🖥️
https://arxiv.org/abs/2603.21235

CellRFT: Reinforcement Fine-Tuning for Single-Cell Perturbation Modeling #SingleCell 🧪🧬🖥️
https://arxiv.org/abs/2609.19970

A five-gene prognostic signature integrating endothelial senescence and lipid metabolism for risk stratification in hepatocellular carcinoma #SingleCell 🧪🧬🖥️
https://www.researchsquare.com/article/rs-10794233/latest

3D Spatial Interactomics Maps the Dynamics of NF-κB Multiprotein Signalosomes in Single Cells #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.09.14.751198v1

DVT-primed neutrophils reshape the brain microenvironment to promote brain metastasis #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.09.15.751589v1

Folic acid polyglutamylation triggers MAP2K5 signaling to induce adipocyte lipid catabolism #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.09.15.751849v1

Spatially distributed growth factor environments for evaluating hydrogel-based CD34+ cell culture conditions #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.09.15.751891v1

PlantRegMoD: An integrative and AI-driven multi-omics database for plant regeneration research #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.09.15.751352v1

Mapping heterogeneity drivers in human PSC-derived limbal stem cell differentiation through single-cell multi-modal analysis #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.09.16.751974v1

miRNA-mediated regulation of lineage plasticity in YY1 knockout pro-B cells #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.09.15.751727v1

Oncogenic fusions induce an extensive cancer-restricted cryptic proteome in Ewing sarcoma #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.09.16.751792v1

Shoutout to co-first authors Ajna Uzuni and Ximi Wang, and to Michael Pressler
@michaelppressler.bsky.social
. Thanks also to the McFaline-Figueroa Lab
@jlmcfalinefigueroa.bsky.social
for their support. Check out our paper!
#GVHD #SingleCell #TCR #SpatialTranscriptomics #Immunology

Cell-specific heteroclinic orbits govern interaction dynamics in inertial microfluidics for circulating tumour cell separation #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.09.15.751739v1

Timing of DNA damage checkpoint adaptation predicts post-mitotic proliferative competence #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.09.15.751746v1

Epigenome Technologies offers an end-to-end Single-Cell Paired-Tag service, the first multiomic assay that simultaneously captures RNA expression and epigenetic marks from preparation to data analysis

#Epigenetics #SingleCell #PairedTag #Multiomics

u.epigenome.us/vyZjktjA

Integration of cell-specific gene expression and chromatin accessibility facilitates localization of neurodegenerative risk in microglia #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.09.15.751821v1

Coupling cell growth to protein secretion enables pooled screening at single-cell resolution in bioreactors #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.09.14.751527v1

AI Scientists for Building Virtual-Cell Models #SingleCell 🧪🧬🖥️
https://www.researchsquare.com/article/rs-10954762/latest

Four-dimensional Gaussian adaptive tomography for aberration-corrected, time-lapse 3D imaging using Fourier light-field microscopy #SingleCell 🧪🧬🖥️
https://www.researchsquare.com/article/rs-10752747/latest