Clustered structural variant hotspots enable oncogenic addiction and plasticity in osteosarcoma #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.09.14.751472v1
@prepub-singlecell.bsky.social
@prepub-singlecell.bsky.socialClustered structural variant hotspots enable oncogenic addiction and plasticity in osteosarcoma #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.09.14.751472v1
@epigenometech.bsky.socialDownload our poster to learn how we used single-cell CUT&Tag and Droplet Paired-Tag to profile PBMCs, generating over 70,000 single-cell profiles and identifying vast numbers of cis-regulatory elements
#Epigenetics #SingleCell #DropletPairedTag #PairedTag #Multiomics
@prepub-singlecell.bsky.socialMonocyte-Mimetic Nanoparticle Delivery of Verteporfin Promotes Plaque-Stabilizing Remodeling in Atherosclerosis #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.09.16.750992v1
@prepub-singlecell.bsky.socialJoint inference of paired dynamical gene regulatory networks reveals distinct cell-state landscapes of neutrophil reprogramming #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.09.16.752194v1
@prepub-singlecell.bsky.socialIn vivo intercellular CRISPR screens using viral proximity barcoding reveal regulators of tumor-immune interactions #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.09.16.752238v1
@prepub-singlecell.bsky.socialssJSD: A fusion of sparsity and spatial information for HiC single-cell clustering #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.09.14.751457v1
@gpbees.bsky.social6/ 📖 Read the full article:
MACS3: A Peak-calling Platform for Bulk and Single-cell Regulatory Genomics
🔗 academic.oup.com/gpb/advance-...
💻 MACS3: github.com/macs3-projec...
#Bioinformatics #Epigenomics #SingleCell #ATACseq #ChIPseq #RegulatoryGenomics
@humancellatlas.orgThe HCA #Breast Cell Atlas integrates #SingleCell data from 287 donors, including people with BRCA1 and BRCA2 mutations, giving insights into cancer risk and potential therapies.
See the Breast Atlas data on the HCA Data Portal buff.ly/awWOUKz
#Genomics #HumanCellAtlas
@prepub-singlecell.bsky.socialPINK1-dependent Mitophagy Mediates CD8+ T Cell Residency and Drives Psoriatic Relapse via CCR4-CCL17/22 Recruitment #SingleCell 🧪🧬🖥️
https://www.researchsquare.com/article/rs-10912733/latest
@prepub-singlecell.bsky.socialPathogenesis and Immune Dynamics of African Swine Fever Virus Across Diverse Suid Species #SingleCell 🧪🧬🖥️
https://www.researchsquare.com/article/rs-10677148/latest
@david-priest.bsky.socialGateLab 0.8.2 is now out! Fable has been absolutely killing it lately on this app. It now has a fully-functioning layout tab where you can assemble your plots. Multiple other improvements like snapping gates. Preprint coming soon.
#flowcytometry #flowjo #cytobank #singlecell #fable
@prepub-singlecell.bsky.socialIntense TP53 pathway selection drives clonal evolution from bone marrow failure to leukemia in ERCC6L2 disease #SingleCell 🧪🧬🖥️
https://www.medrxiv.org/content/10.64898/2026.09.16.26363199v1
@prepub-singlecell.bsky.socialSerotonergic circuit architecture underlies sex dimorphism in anxiogenic states #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.09.15.751692v1
@prepub-singlecell.bsky.socialA robust, scalable K-statistic for quantifying immune cell clustering in spatial proteomics data #SingleCell 🧪🧬🖥️
https://arxiv.org/abs/2412.08498
@prepub-singlecell.bsky.socialHarmonised benchmarking of foundation models for single-cell and spatial transcriptomics reveals context-dependent generalisation #SingleCell 🧪🧬🖥️
https://arxiv.org/abs/2607.17227
@prepub-singlecell.bsky.socialUnicellular and Multicellular Modes of Selection Impose Distinct Constraints on Cellular Phenotype Evolution #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.09.16.751889v1
@prepub-singlecell.bsky.socialRapid evolution of cone identity and retinal topography in deep-water crater lake cichlids #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.09.16.751957v1
@prepub-singlecell.bsky.socialGlobal, single-cell-resolution of antiviral defenses in marine prokaryoplankton #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.09.15.751803v1
@prepub-singlecell.bsky.socialDiffDomain-Spectrum identifies structurally reorganized TADs from sparse aggregated single-cell Hi-C contact maps #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.09.15.751728v1
@prepub-singlecell.bsky.socialTranscriptomic Models for Immunotherapy Response Prediction Show Limited Cross-cohort Generalisability #SingleCell 🧪🧬🖥️
https://arxiv.org/abs/2604.05478