Single-cell transcriptomics of Encephalitozoon intestinalis infection in Caco-2 and Vero cells #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.09.18.752679v1

Modeling lung adenocarcinoma using layer-by-layer nanoparticles mitigates innate immune cell activation #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.09.14.751530v1

SMORE: joint dimension reduction and cell population discovery on single-cell methylome data #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.09.14.751514v1

Transcriptomic Models for Immunotherapy Response Prediction Show Limited Cross-cohort Generalisability #SingleCell 🧪🧬🖥️
https://arxiv.org/abs/2604.05478

From In Silico to In Vitro: A Comprehensive Guide to Validating Bioinformatics Findings #SingleCell 🧪🧬🖥️
https://arxiv.org/abs/2502.03478

A Hybrid Computational Intelligence Framework for scRNA-seq Imputation: Integrating scRecover and Random Forests #SingleCell 🧪🧬🖥️
https://arxiv.org/abs/2511.16923

Notrix: Understanding Machine Learning Solutions Across Computational Notebooks at Scale #SingleCell 🧪🧬🖥️
https://arxiv.org/abs/2609.21775

A self-limiting, TREM2-dependent anabolic program confers microglial resilience in Alzheimer's disease #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.09.16.752098v1

High-altitude exercise orchestrates a divergent immune landscape: cytotoxic suppression, humoral compensation, and neutrophil functional reprogramming. #SingleCell 🧪🧬🖥️
https://www.medrxiv.org/content/10.64898/2026.09.17.26363363v1

Weekly reads 14/09/26 :
Spatial multiomics, scarless editing, and xenocortical mice: advances across scales and systems

behindthebioinformatics.substack.com/p/weekly-rea...

#SpatialMultiomics #SingleCell #CRISPR #LineageTracing #Neuroscience #CancerResearch

Cellular code for mnemonic pattern separation in the human hippocampus is revealed by false memories #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.09.18.752786v1

A lifespan single-cell atlas of the human developing hippocampus benchmarks familial Alzheimer's disease brain organoids. #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.09.18.752796v1

Evolution of new cerebellar nuclei by excitatory progenitor diversification in the early rhombic lip #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.09.17.751883v1

Multi-model biological and sequence information fusion for gene regulatory network inference from single-cell transcriptomics #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.09.13.751326v1

Single-cell profiling reveals disruption of cell-cycle homeostasis following JDP2 depletion in colorectal epithelial cells #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.09.14.751340v1

Single-Cell Study Designs Are Systematically Underpowered for Small-Effect Genes #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.09.17.752063v1

Dermal bone remodelling by invasive osteoblasts evolved in stem gnathostomes #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.09.16.752034v1

Rethinking the Benign Nature of Class II Lupus Nephritis #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.09.13.751280v1

Post-selection inference in testing for phenotypic differences with scRNA-Seq #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.09.17.752411v1

Single-cell DNA cytometry with magnetic- and fluorescence-activated bead sorting #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.09.12.751168v1