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@nsrhighlights.bsky.socialSep 15, 2026, 12:15 PM

In mice after stroke, stimulating brain support cells before rehabilitation enhanced recovery of paw movement during later training.
📅 Published: Sep 13, 2026
🔗 https://doi.org/10.1016/j.neures.2026.105120
#NeuroscienceResearch #Neuroscience

和風の研究室で、黒いマウスが木の窓から前足を伸ばして餌を取ろうとし、猫の探検家が観察しています。別の和紙屏風にはアストロサイトを表す星形の細胞。細胞への刺激と、その後の訓練を分けた概念画で、顕微鏡像や治療効果の再現ではありません。
@nsrhighlights.bsky.socialSep 15, 2026, 12:15 PM

脳卒中を起こしたマウスで、神経を支える細胞を先に刺激すると、その後の訓練による前足の動きの回復が大きくなりました。
📅 2026年9月13日公開
🔗 https://doi.org/10.1016/j.neures.2026.105120
#NeuroscienceResearch #Neuroscience

和風の研究室で、黒いマウスが木の窓から前足を伸ばして餌を取ろうとし、猫の探検家が観察しています。別の和紙屏風にはアストロサイトを表す星形の細胞。細胞への刺激と、その後の訓練を分けた概念画で、顕微鏡像や治療効果の再現ではありません。
@nsrhighlights.bsky.socialSep 14, 2026, 12:15 PM

After fracture, persistent pain in mice involved spinal DHCR7-dependent cholesterol buildup feeding into the immune signal MCP-3 and astrocyte pathways.

https://doi.org/10.1016/j.neures.2026.105064
#NeuroscienceResearch #Neuroscience #Pain

Japanese painterly NSR cover showing a recognizable spinal dorsal-horn cross-section; activated astrocyte-like forms around a DHCR7-cholesterol source; and MCP-3 signal flow toward a measured pain-sensitivity gate. The canonical explorer examines the sequence at three checkpoints without turning it into a human treatment pathway. A small washi banner reads Neuroscience Research.
@nsrhighlights.bsky.socialSep 14, 2026, 12:15 PM

骨折後の痛みが長引くとき、脊髄では脂質代謝も変わっていました。マウスでは、コレステロール合成酵素DHCR7に依存した蓄積が起こり、免疫情報分子MCP-3とアストロサイトの信号を通じて痛みの持続を支えました。

https://doi.org/10.1016/j.neures.2026.105064
#NeuroscienceResearch #Neuroscience #Pain

Japanese painterly NSR cover showing a recognizable spinal dorsal-horn cross-section; activated astrocyte-like forms around a DHCR7-cholesterol source; and MCP-3 signal flow toward a measured pain-sensitivity gate. The canonical explorer examines the sequence at three checkpoints without turning it into a human treatment pathway. A small washi banner reads Neuroscience Research.
@nsrhighlights.bsky.socialSep 13, 2026, 12:15 PM

In the new Igfn1iCre mouse line, many labeled bipolar cells were type-7-like during development, while adult labeling spread across a wider mix of retinal cell types.

https://doi.org/10.1016/j.neures.2026.105067
#NeuroscienceResearch #Neuroscience #Retina

Japanese painterly NSR cover showing a recognizable layered retina; type-7-like bipolar cells reaching stratum S4; and a developmental-to-adult widening of labeled cell classes. The canonical explorer follows one bipolar cell from the outer layer to its S4 terminal and then compares ages. A small washi banner reads Neuroscience Research.
@nsrhighlights.bsky.socialSep 13, 2026, 12:15 PM

網膜細胞を標識する道具は、年齢で使い勝手が変わります。Igfn1iCreマウスでは、発達期に標識された双極細胞の多くがtype-7らしい形を示しましたが、成体では多様な網膜細胞が標識されました。

https://doi.org/10.1016/j.neures.2026.105067
#NeuroscienceResearch #Neuroscience #Retina

Japanese painterly NSR cover showing a recognizable layered retina; type-7-like bipolar cells reaching stratum S4; and a developmental-to-adult widening of labeled cell classes. The canonical explorer follows one bipolar cell from the outer layer to its S4 terminal and then compares ages. A small washi banner reads Neuroscience Research.
@nsrhighlights.bsky.socialSep 11, 2026, 12:15 PM

Proximity labeling near signal-releasing axon endings in cultured neurons found about 500 bouton-enriched proteins, including established presynaptic machinery.

https://doi.org/10.1016/j.neures.2026.105070
#NeuroscienceResearch #Neuroscience #Proteomics

Japanese painterly NSR cover showing a recognizable axon with several presynaptic boutons; a tight proximity-labeling halo around boutons; and candidate protein groups arranged outside the axon-wide comparator. The canonical explorer collects only markers falling within the bouton-centered halo. A small washi banner reads Neuroscience Research.
@nsrhighlights.bsky.socialSep 11, 2026, 12:15 PM

神経細胞が次の細胞へ信号を渡す軸索末端には、どんなタンパク質が集まる？ 生きた培養神経で近くの分子に印を付けると、既知のシナプス装置を含む約500の濃縮候補が見つかりました。

https://doi.org/10.1016/j.neures.2026.105070
#NeuroscienceResearch #Neuroscience #Proteomics

Japanese painterly NSR cover showing a recognizable axon with several presynaptic boutons; a tight proximity-labeling halo around boutons; and candidate protein groups arranged outside the axon-wide comparator. The canonical explorer collects only markers falling within the bouton-centered halo. A small washi banner reads Neuroscience Research.
@danafoundation.bsky.socialSep 10, 2026, 6:15 PM

When Walter Koroshetz began his career, neurology was considered “diagnose and adios.” Today, advances in neuroscience are transforming what is possible for people with neurological conditions.

#neursociety #neuroethics #neuroscienceresearch #neurotech

@nsrhighlights.bsky.socialSep 10, 2026, 12:15 PM

Does a candidate drug for neural recovery directly touch its proposed protein target? NMR measurements of molecular contact supported binding between edonerpic maleate and CRMP2.

https://doi.org/10.1016/j.neures.2026.105068
#NeuroscienceResearch #Neuroscience #NMR

Japanese painterly NSR cover showing one folded CRMP2 protein-like form; one small edonerpic ligand-like form near a binding surface; and NMR signal rings that attenuate without becoming a fake spectrum. The canonical explorer holds a listening trumpet near the interaction and observes the fading signal rings. A small washi banner reads Neuroscience Research.
@nsrhighlights.bsky.socialSep 10, 2026, 12:15 PM

候補薬は標的タンパク質に本当に触れるのでしょうか。神経機能回復の候補薬edonerpic maleateと標的候補CRMP2を、分子の接触を調べるNMRで測ると、直接結合を支持する結果が得られました。

https://doi.org/10.1016/j.neures.2026.105068
#NeuroscienceResearch #Neuroscience #NMR

Japanese painterly NSR cover showing one folded CRMP2 protein-like form; one small edonerpic ligand-like form near a binding surface; and NMR signal rings that attenuate without becoming a fake spectrum. The canonical explorer holds a listening trumpet near the interaction and observes the fading signal rings. A small washi banner reads Neuroscience Research.
@nsrhighlights.bsky.socialSep 9, 2026, 12:15 PM

In mouse embryos, temporarily reducing host microglia before transplantation allowed more donor cells to leave the ventricle and enter brain tissue.

https://doi.org/10.1016/j.neures.2026.105071
#NeuroscienceResearch #Neuroscience #Microglia

Japanese painterly NSR cover showing an embryonic ventricular boundary; donor microglia-like cells on both sides of that boundary; and greater parenchymal entry after host-cell depletion. The canonical explorer watches donor cells cross the ventricular edge and marks how far they travel. A small washi banner reads Neuroscience Research.
@nsrhighlights.bsky.socialSep 9, 2026, 12:15 PM

発達中の脳へ細胞を移植するとき、先に「居場所」を空けると何が変わる？ 胎生マウスで宿主ミクログリアを一時的に減らすと、移植した細胞が脳室に留まらず、脳組織へ入る数が増えました。

https://doi.org/10.1016/j.neures.2026.105071
#NeuroscienceResearch #Neuroscience #Microglia

Japanese painterly NSR cover showing an embryonic ventricular boundary; donor microglia-like cells on both sides of that boundary; and greater parenchymal entry after host-cell depletion. The canonical explorer watches donor cells cross the ventricular edge and marks how far they travel. A small washi banner reads Neuroscience Research.
@nsrhighlights.bsky.socialSep 8, 2026, 12:15 PM

In mouse hippocampal CA1, synapse-related markers followed different developmental and prenatal-valproate patterns depending on layer and dorsoventral position.

https://doi.org/10.1016/j.neures.2026.105066
#NeuroscienceResearch #Neuroscience #Synapses

Japanese painterly NSR cover showing a recognizable layered CA1 arc; separate PSD95-like and gephyrin-like puncta concepts; and three layers arranged across four developmental time markers. The canonical explorer uses a transparent coordinate grid to compare puncta across CA1 layers. A small washi banner reads Neuroscience Research.
@nsrhighlights.bsky.socialSep 8, 2026, 12:15 PM

海馬CA1の変化を平均してしまうと、層ごとの違いは消えてしまいます。マウス組織を層の座標に沿って調べると、シナプスに関わる目印の発達と、胎生期バルプロ酸曝露後の変化は場所ごとに異なりました。

https://doi.org/10.1016/j.neures.2026.105066
#NeuroscienceResearch #Neuroscience #Synapses

Japanese painterly NSR cover showing a recognizable layered CA1 arc; separate PSD95-like and gephyrin-like puncta concepts; and three layers arranged across four developmental time markers. The canonical explorer uses a transparent coordinate grid to compare puncta across CA1 layers. A small washi banner reads Neuroscience Research.
@nsrhighlights.bsky.socialSep 7, 2026, 12:15 PM

Can structural MRI distinguish ADHD from typical development without predefined brain regions? A Vision Transformer outperformed a baseline CNN and a standard region-based method.

https://doi.org/10.1016/j.neures.2026.105054
#NeuroscienceResearch #Neuroscience #NeuroAI

Japanese washi-style night observatory: the canonical cat explorer counts eleven simple brain-slice outline tiles while a larger slice stack and a compact rack feed an indigo patch grid. Two supported regions on a painterly brain outline glow amber and vermilion, beside a Neuroscience Research banner.
@nsrhighlights.bsky.socialSep 7, 2026, 12:15 PM

脳を決まった領域に切り分けなくても、構造MRIからADHDと定型発達を分類できる？ 画像全体の関係を学ぶモデルは、基準にした画像認識AIと脳領域ごとの従来法より高い分類性能を示しました。

https://doi.org/10.1016/j.neures.2026.105054
#NeuroscienceResearch #Neuroscience #NeuroAI

Japanese washi-style night observatory: the canonical cat explorer counts eleven simple brain-slice outline tiles while a larger slice stack and a compact rack feed an indigo patch grid. Two supported regions on a painterly brain outline glow amber and vermilion, beside a Neuroscience Research banner.
@nsrhighlights.bsky.socialSep 6, 2026, 12:15 PM

In mice, cells expressing the adhesion molecule Pcdhβ3 showed coordinated activity across cortex and hippocampus and recruited matching cells through their projections.

https://doi.org/10.1016/j.neures.2026.105081
#NeuroscienceResearch #Neuroscience #Memory

Japanese painterly NSR cover showing recognizable entorhinal and hippocampal regions; matching Pcdhβ3-defined cell populations; and a projection-dependent bridge that is present but not an invented full circuit. The canonical explorer compares matching cell lanterns on both sides of the projection boundary. A small washi banner reads Neuroscience Research.
@nsrhighlights.bsky.socialSep 6, 2026, 12:15 PM

海馬と皮質をまたぐ神経集団は、同じ「細胞の名札」を共有するのでしょうか。マウスでは、Pcdhβ3という接着分子を持つ細胞の活動が領域間で対応し、投射を通じて同じ型の細胞が応答しました。

https://doi.org/10.1016/j.neures.2026.105081
#NeuroscienceResearch #Neuroscience #Memory

Japanese painterly NSR cover showing recognizable entorhinal and hippocampal regions; matching Pcdhβ3-defined cell populations; and a projection-dependent bridge that is present but not an invented full circuit. The canonical explorer compares matching cell lanterns on both sides of the projection boundary. A small washi banner reads Neuroscience Research.
@nsrhighlights.bsky.socialSep 5, 2026, 8:42 AM

Social context changed how the same tutor song was represented in juvenile zebra finches: some responses in the reward-related midbrain VTA/SNc grew stronger, while others grew weaker.

https://doi.org/10.1016/j.neures.2026.105108
#NeuroscienceResearch #Neuroscience

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