(J Chrom A) Mass Spectrometry‑Based Chemoproteomics for Modern Drug Screening: A Critical Review and the 3M Framework (Match–Map–Mine): Publication date: Available online 8 October 2026

Source: Journal of Chromatography A

Author(s): Fuyan Liu, Haolin Zhang, Ying Qu, Haojie… #JChrom #MassSpecRSS

(JASMS) TherMIDAS: An Integrated
Data Acquisition System for
FT-ICR Mass Spectrometry: AbstractOver
30 years ago, the Modular ICR Data Acquisition System
(MIDAS)
was assembled, developed, and deployed on the then-new Fourier transform
ion cyclotron resonance mass spectrometry… (RSS) #MassSpecRSS

(JASMS) IsoPairFinder: A Computational
Workflow for Prioritizing
LC–MS Feature Pairs Representing Candidate Microbial Pathway
Intermediates from Stable Isotope Tracing Metabolomics: AbstractFunctional annotation of microbial genes lags behind
the pace of
genome sequencing,… (RSS) #MassSpecRSS

(JASMS) Influence of Gas Flow on Ion Transport in PTR-MS Drift
Tubes Using an Electro-Hydrodynamic Coupled Model: AbstractProton transfer reaction
mass spectrometry (PTR-MS) is widely used
for the real-time detection of volatile organic compounds (VOCs).
Previous efforts to… (RSS) #MassSpecRSS

(BioRxiv All) Proteomic Characterization of Prostate Cancer Bone Metastasis Subtypes Defines Progressive Remodeling States of the Bone-Tumor Microenvironment: Prostate cancer (PC) bone metastases (PCBM) are a debilitating disease morbidity that primarily affects the axial… #BioRxiv #MassSpecRSS

(BioRxiv All) Pharmacokinetic properties of Ogerin and its regulation of post-ischemia signaling in mice: Ogerin, a positive regulator of GPR68, reduces infarct volume and attenuates blood-brain barrier (BBB) leakage post transient middle cerebral artery occlusion (tMCAO).… #BioRxiv #MassSpecRSS

(BioRxiv All) Pannexin 1 Ablation Disrupts Cell Cycle Progression and Compromises the Structure of Melanoma Tumours: Pannexin 1 (PANX1) is a channel-forming glycoprotein that has been implicated in regulating melanoma cell properties such as growth, migration, and invasion.… #BioRxiv #MassSpecRSS

(ChemRxiv) Multinotch Isolation Enables Efficient Native Top-down Mass Spectrometry of Proteins in Complex Mixtures.: Accurate identification of intact proteoforms and their complexes directly from heterogenous biological samples is essential to understand their role in health and… #MassSpecRSS

(ChemRxiv) Research Progress and Applications of the Fundamental Principles of Soft Ionization Mass Spectrometry: (1. Guangdong Huisheng Testing Technology Co., Ltd.) Abstract: Soft ionization mass spectrometry is widely applied in fields such as pharmaceuticals, cosmetics,… #MassSpecRSS

High-throughput spatial proteomics from cellular to subcellular scales via a hanging droplet workflow #nature #MassSpecRSS

(BioRxiv All) ATP synthase deficiency promotes prolonged hydrogenproduction in Chlamydomonas: Photosynthetic electron transport is tightly regulated to balance ATP and NADPH production and prevent over-reduction of the photosynthetic machinery. How this balance is maintained… #BioRxiv #MassSpecRSS

(J Mass Spectrom) Correction to “Mass Spectral Investigation of Carbamates using EI and CI Techniques”: Journal of Mass Spectrometry, Volume 61, Issue 10, October 2026. #JMassSpectrom #MassSpecRSS

(J Sep Sci) Green Sorptive Sampling Coupled With UHPLC–IMS–MS and GC×GC–TOFMS for Characterization of Migrating Substances From Plastic Food Contact Materials: A green PDMS sorptive sampling loop coupled with complementary liquid and gas chromatography–mass spectrometry… #JSepSci #MassSpecRSS

(J Sep Sci) In‐situ Grown Covalent Organic Frameworks on Electrospun Nanofibers for Efficient Enrichment and Determination of Organophosphate Esters in Biodegradable Plastics: ABSTRACT

In this work, a covalent organic framework (COF)-based nanofibrous composite… #JSepSci #MassSpecRSS

PI3Kδ is selectively inhibited by roginolisib by stabilizing the C-terminal helix kα12 #nature #MassSpecRSS

(JPR) Targeted Analysis
of >1500 Plasma Proteoforms via
Individual Ion Mass Spectrometry: AbstractPlasma proteomics has emerged as a powerful approach
for interrogating
human biology, identifying disease-associated proteomic changes, and
advancing precision diagnostics. In recent… #MassSpecRSS

(A Chem) DESI-Enabled Signature-Ion-Guided Natural Product Imaging (DESIGNi) for Rapid Screening of Aromatic Acylated Derivatives in Plant Tissues: AbstractMass spectrometry imaging (MSI) enables in situ visualization of small-molecule distributions in plants. However, MSI data… #MassSpecRSS

(A Chem) Lost in Overlap: Mapping Local Composition Landscapes to Predict the Upper Measurable Mass Limit of Copolymers and Terpolymers by MALDI-TOF MS: AbstractMatrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) is widely used for polymer… #MassSpecRSS

(A Chem) 96-Sample Parallel BioSPME-DART-MS Platform for Rapid Screening of Fentanyl and its Analogues in Biofluids: AbstractSolid-phase microextraction (SPME) with biocompatible coating material is highly compatible with ambient mass spectrometry (AMS), such as direct analysis in real… #MassSpecRSS

(A Chem) Automated Electrostatic Attraction/Repulsion Hydrophilic Interaction Liquid Chromatography Screening for Polar and Charged Analytes in Complex Matrices: AbstractElectrostatic repulsion hydrophilic interaction liquid chromatography (ERLIC) provides unique selectivity for highly… #MassSpecRSS