The Cyanobacterial dnaX Intein Encodes an Out-of-Frame Homing Endonuclease and is Sporadically Distributed in the Phylum #SingleCell 🧪🧬🖥️
https://www.researchsquare.com/article/rs-10898355/latest

Billion-parameter AI cell models keep losing to plain linear maths on core biology tasks. A wave of 2025-2026 benchmarks is forcing a reckoning in computational biology. What does honest evaluation actually show? #Bioinformatics #AIinScience #SingleCell

artificialscience.org/2026/09/simp...

Robust Inference of Phage Host Infection Dynamics from Sparse Single-Cell Transcriptomic Profiles in Pseudomonas aeruginosa #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.09.24.752076v1

OmicsResonance: An LLM-assisted cloud ecosystem for interactiveand reproducible single-cell transcriptomic analysis #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.09.20.753054v1

β3-Integrin controls pericyte metabolic states and shapes tumour-stromal metabolic crosstalk in breast cancer #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.09.21.751368v1

sfate: Schur-free, target-conditioned absorption probabilities for scalable single-cell fate analysis #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.09.19.752930v1

MERFISHEYES: Web-based Visualization and Sharing Platform for Single-cell and Single-molecule Spatial Transcriptomics #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.09.20.753029v1

PerturbBridge: Conditional Latent Schr\"{o}dinger Bridge for Single-Cell Perturbation Prediction #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.09.24.754259v1

OmiCoreTumorDetector: an open, molecularly validated model for mapping tumour regions in colorectal cancer H&E sections #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.09.21.753083v1

Robustness measures for cell type classification in single-cell RNA-seq datasets of kidney organoids #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.09.20.752971v1

A single-nuclei multiomics resource across four brain regions prioritises human neural cell types influencing brain-related traits #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.09.24.754059v1

ILDR2 is a conserved podocyte stress marker uncoupled from glomerular barrier function and local immune modulation​ #SingleCell 🧪🧬🖥️
https://www.researchsquare.com/article/rs-10837673/latest

The tumor microenvironment landscape in lung adenocarcinoma with spatial transcriptomic mapping #SingleCell 🧪🧬🖥️
https://www.researchsquare.com/article/rs-10946821/latest

MiCAS: Mixture-based Cell Annotation with Open-Set Recognition for scRNA-seq Data #SingleCell 🧪🧬🖥️
https://www.researchsquare.com/article/rs-10438566/latest

Ductal myofibroblasts reactivate contractile program to stabilize alveolar architecture during lung regeneration #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.09.23.753969v1

APOA1 links a late fetal epithelial program to colonic maturation and injury responses #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.09.24.754040v1

Deep generative embeddings of gene expression and splicing reposition the interpretation of single-cell transcriptomic signatures #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.09.23.753495v1

Context-specific genetic interaction mapping reveals combinatorial KRAS/FGFR dependence in pancreatic cancer #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.09.24.754062v1

Human memory CD4+ T cells recognize non-infected macrophage bystanders exposed to Mycobacterium tuberculosis-infected cells #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.09.19.752467v1

Cell-Lens: Advancing LLM Reasoning at Single-Cell Resolution #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.09.19.752842v1