explore | Grilled Cheese

A phytoscreen of 43 fruits/vegetables revealed garlic as a key deterrent of mating and egg laying in Drosophila and mosquitoes. Diallyl disulfide disrupts these behaviors! 🍏🦟 PMID:41999745, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S0092-8674(26)00338-7 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪

New paleoproteomic analysis of 23 H. naledi dental enamel specimens from 20 individuals reveals no male markers, suggesting a single-sex sample in a unique population. PMID:42341758, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S0092-8674(26)00644-6 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪

Unlocking myxobacteria: New genetic tools and a heterologous chassis boost bioactive compound discovery. MxRecET recombinases enhance genome editing in Myxococcus xanthus DK1622. PMID:42373632, Nat Commun 2026, @NatureComms https://doi.org/10.1038/s41467-026-74908-x #Medsky #Pharmsky #RNA #ASHG 🧪

Check out our advanced review Toward mapping spatitemporal resolved transcriptomes and RNA-protein interactions wires.onlinelibrary.wiley.com/doi/10.1002/... that we wrote with my postdoc Antto and that was inspired by cool experiments ongoing in the lab. #rna @aboakademi.bsky.social

Arabidopsis seeds pack histone variant H2B.8, arranging 3D nuclear space. Upon imbibition, H2B.8 is evicted, hinting at chromatin reprogramming in seed-to-seedling transition! PMID:42373623, Nat Commun 2026, @NatureComms https://doi.org/10.1038/s41467-026-74230-6 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪

Allergen exposure in lung epithelial cells triggers PAR1-dependent ferritinophagy, boosting labile iron levels. This iron is crucial for noncanonical, protease-independent GSDMD activation, driving IL-33… PMID:42361797, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S0092-8674(26)00653-7 #RNA 🧪

71F with speech, gait issues, hearing loss found with infratentorial superficial siderosis & T-spinal cord cleft. Fascinating case! PMID:42371616, JAMA Neurol 2026, @JAMANeuro https://doi.org/10.1001/jamaneurol.2026.1992 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪

Discoveries in viral replication: UL9 protein of HSV-1 forms DNA tethers and loops at oriS. A direct view into herpesvirus genome replication mechanisms. PMID:42373616, Nat Commun 2026, @NatureComms https://doi.org/10.1038/s41467-026-74361-w #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪

2'3'-cGAMP activates a unique 3TM-SMODS model promoting membrane shearing in anti-phage immunity, revealing novel insights into prokaryotic antiviral defenses. PMID:41999741, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S0092-8674(26)00344-2 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪

12 cave lion genomes from over 100,000 years reveal distinct lineages from modern lions, with unique variants and signs of ancient gene flow. Evolutionary secrets uncovered! PMID:42235515, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S0092-8674(26)00524-6 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪

Hot off the press from the Watts & Khvorova labs: Albumin-binding dendrimer-conjugated siRNA enables safe and effective gene silencing throughout the central nervous system buff.ly/FUvJ0hf
#RNA #RNATherapeutics

Noninvasive neuroprosthesis breakthrough: Brain2Qwerty decodes sentences from brainwaves in 35 volunteers. High potential with no surgery needed! #Neurotech PMID:42374156, Nat Neurosci 2026, @NatureNeuro https://doi.org/10.1038/s41593-026-02303-2 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪

Autoimmune encephalitis research hits a plateau in novel autoantibody discovery. Shifting focus may better aid patients. PMID:42371641, JAMA Neurol 2026, @JAMANeuro https://doi.org/10.1001/jamaneurol.2026.1659 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪

A new model analyzes mammalian cortical connectomes, revealing that spatial constraints design unique connectivity profiles across regions in complex networks. PMID:42361798, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S0092-8674(26)00648-3 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪

Study of 3.6M+ adults in Chile shows severe COVID-19 may increase TB risk. Urgent need for monitoring post-COVID recovery! Let's discuss the implications. PMID:42373634, Nat Commun 2026, @NatureComms https://doi.org/10.1038/s41467-026-74528-5 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪

Study identifies >1,000 somatic variants in 311 AD brain samples, linking cancer driver genes, clonal hematopoiesis, and neuroinflammation via microglia-like cells. PMID:42019491, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S0092-8674(26)00341-7 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪

Thank you @shihcheng.bsky.social for sharing this elegant study, fusing Ca²⁺ imaging, morphology & in situ transcriptomics for 30 neurons.
We are pleased to find and highlight research like this.
Follow @academaxjournals.bsky.social for similar #STEM studies.

#MedEdsky #RNA #ASHG #ESHG

#OnThisDay in 1985, Frisco and Robert planned Frisco’s story, and Robert filled Anna in after bringing her and Robin home #RnA #FnF #ClassicGH #GH #GeneralHospital