An amyloid-β/APP regulatory layer in human brown adipocyte recruitment identifies repurposable drugs for thermogenic fat expansion #NeuroDegeneration 🧪🧠
https://www.biorxiv.org/content/10.64898/2026.10.02.754417v1

Somatic TARDBP variants identified in human brain with FTLD-TDP-C disrupt morphology and microglia numbers in zebrafish #NeuroDegeneration 🧪🧠
https://link.springer.com/10.1186/s40478-026-02417-5

High frequency transcranial pulsed current stimulation improves quality of life in Parkinson’s disease: A randomized controlled trial #NeuroDegeneration 🧪🧠
https://www.researchsquare.com/article/rs-10834572/latest

Association of Treatment Satisfaction with Quality of Life and All-Cause Mortality in Hemodialysis Patients #NeuroDegeneration 🧪🧠
https://www.researchsquare.com/article/rs-10856845/latest

Interleukin-17 Inhibits Myelin-Related Protein Expression in Human Oligodendrocytes via NF-κB/STAT3 Signaling: Implications for Bipolar Disorder #NeuroDegeneration 🧪🧠
https://www.researchsquare.com/article/rs-10109040/latest

White matter hyperintensities partly mediate genetically predicted blood pressure effects on vascular dementia #NeuroDegeneration 🧪🧠
https://www.researchsquare.com/article/rs-11236498/latest

Structure-Based Virtual Screening of Bioactive Natural Polyphenols Towards Lead Discovery of the RAGE Inhibitor for the Eradication of Diabetes-Associated Pathology #NeuroDegeneration 🧪🧠
https://www.researchsquare.com/article/rs-10717739/latest

DNA Sequence and Substrate Concentration Shape TET2-Mediated Oxidation of CpG and Non-CpG Methylcytosines #NeuroDegeneration 🧪🧠
https://www.researchsquare.com/article/rs-10974122/latest

Substituent Effects on Electronic Properties and Acetylcholinesterase Inhibitory Potential of Donepezil Analogues: A DFT, Molecular Docking, and ADMET Study with Dynamics Validation of the Lead Candidate #NeuroDegeneration 🧪🧠
https://www.researchsquare.com/article/rs-11082767/latest

Singlet-filtered 1 H-MRS at 3 T yields phantom-calibrated apparent regional glutamate values in healthy adults and compartmental glutamate alterations in glioma: a prospective observational study #NeuroDegeneration 🧪🧠
https://www.researchsquare.com/article/rs-10871783/latest

Genome fragility can shape disease risk.
This review highlights PARK2 as a fragile-site gene that links replication stress, #neurodegeneration, and #cancer, revealing its potential as both a biomarker and #PrecisionMedicine target.
#GenesAndDiseases: doi.org/10.1016/j.ge...

AI-Powered Fault Prediction in 1100-kV Power Transmission Systems: From Algorithm-Driven Protection to Intelligent, Predictive Systems #NeuroDegeneration 🧪🧠
https://www.researchsquare.com/article/rs-11227473/latest

Blood Free Carnitine Level is an Independent Determinant of Erythrocyte Membrane Homogeneity and Osmotic Resistance in Maintenance Hemodialysis Patients #NeuroDegeneration 🧪🧠
https://www.researchsquare.com/article/rs-11079562/latest

HSP70 activates selective autophagy via UBQLN2 to alleviate hSOD1G93A-mediated neurotoxicity in NSC-34 cellular model of ALS #NeuroDegeneration 🧪🧠
https://www.researchsquare.com/article/rs-10866091/latest

Study of blood linear RNA nominates CD55 and DLD as early-stage biomarkers for Parkinson's disease #NeuroDegeneration 🧪🧠
http://doi.org/10.1093/brain/awag014

Missense variants in TUBA4A cause myo-tubulinopathies #NeuroDegeneration 🧪🧠
http://doi.org/10.1093/brain/awag059

BTK inhibition suppresses neuroinflammation and neurodegeneration in amyotrophic lateral sclerosis #NeuroDegeneration 🧪🧠
http://doi.org/10.1093/brain/awag070

P2X7 receptor-mediated IL-1β release by human brain tissue: the impact of CNS-penetrant potential therapeutics #NeuroDegeneration 🧪🧠
http://doi.org/10.1093/brain/awag068

Constitutive neuronal expression and disease-associated upregulation of chitinases in amyotrophic lateral sclerosis #NeuroDegeneration 🧪🧠
http://doi.org/10.1093/brain/awag083

Berbamine hydrochloride as a brain-penetrant galectin-3 inhibitor in a model of Huntington’s disease #NeuroDegeneration 🧪🧠
http://doi.org/10.1093/brain/awag069