Kinesins as dynamic drug targets: structural insights and emerging therapeutic strategies pubmed.ncbi.nlm.nih.gov/42773013/ #cryoEM

De novo design of semisynthetic conduction pores pubmed.ncbi.nlm.nih.gov/42768128/ #cryoEM

Cryo-EM Pipeline for Actin Filament End Structures pubmed.ncbi.nlm.nih.gov/42769743/ #cryoEM

BaCas12a3 represents a new subtype of type V CRISPR effector with collateral activity toward tRNA pubmed.ncbi.nlm.nih.gov/42770331/ #cryoEM

Structures of distinct human acetylcholinesterase tetramer forms in complex with synaptic anchoring proteins pubmed.ncbi.nlm.nih.gov/42772275/ #cryoEM

Very happy to share the first paper from our lab, out now in Nature Communications!🎉🥳

Structural basis of step II Spliced Leader RNA trans-splicing in trypanosomatid parasites 🧬🔬

🔗 www.nature.com/articles/s41...

@natcomms.nature.com @universitedeliege.bsky.social @rockefeller.edu #cryoEM #cryo-EM

Molecular basis of metal transport by human ZnT10 pubmed.ncbi.nlm.nih.gov/42772276/ #cryoEM

Structural insights into target detection by the Serratia type III CRISPR complex and its deployment in SNP identification pubmed.ncbi.nlm.nih.gov/42772556/ #cryoEM

Structural basis of isoform-specific cAMP regulation and autoinhibition in hyperpolarization-activated cyclic nucleotide-gated channels pubmed.ncbi.nlm.nih.gov/42772566/ #cryoEM

FRET-guided integrative modeling resolves Mg2+-dependent RNA tertiary-contact formation www.biorxiv.org/content/10.64898/2026.09.17.752353v1 #cryoEM

Frank Nijpels from VitriMatics paid us a visit today. Not only did he repair our broken VitroBot Mark IV and returned it in person, he also brought some extremely cool tools ❄️ for reliable cryo-EM grid freezing 🔬.
Check out the VitriClip and the SupraBlot at vitrimatics.com.
#cryoEM #cryoET

An N-Terminally Acetylated Degron Specifically Recognized by the CTLHMKLN1-FAM72A E3 Ubiquitin Ligase for Regulatory Protein Degradation www.biorxiv.org/content/10.64898/2026.09.19.752822v1 #cryoEM

Structural basis of ligand-selective transcriptional activation in the MerR-family antibiotic resistance regulator AlbA www.biorxiv.org/content/10.64898/2026.09.21.753095v1 #cryoEM

🔎 A classic #cryoEM particle curation conundrum: 2D or 3D classification?

"Decoy Classification" using Heterogeneous Refinement in #CryoSPARC curates particles directly in 3D, helping remove junk particles while preserving valuable views.

Read more in the CryoSPARC Blog 👉 bit.ly/3SXfwS0

Programmable gold nanoparticle conjugates enable precise AMPA receptor localization at brain synapses by cryo-ET www.biorxiv.org/content/10.64898/2026.09.18.752772v1 #cryoEM

Structural basis of interaction between Pol1 and DnaN from Mycobacterium tuberculosis www.biorxiv.org/content/10.64898/2026.09.19.751633v1 #cryoEM

H2A.Z-H2B.V nucleosomes form a specialised scaffold for transcription initiation in Trypanosoma brucei www.biorxiv.org/content/10.64898/2026.09.18.752700v1 #cryoEM

Molecular Architecture of the Human GCN1-ABCF3 Ribosome Collision Sensor www.biorxiv.org/content/10.64898/2026.09.19.752920v1 #cryoEM

Molecular architecture responsible for specific inhibition of oncogenic PI3Kα mutants by RLY-2608 and STX-478 pubmed.ncbi.nlm.nih.gov/42764855/ #cryoEM