Multilevel Mechanisms by Which Membrane Transport Proteins Regulate Plant Responses to Heavy Metal Stress: From Ion Perception and Uptake Control to Systemic Signaling and Translational Perspectives pubmed.ncbi.nlm.nih.gov/42782210/ #cryoEM

Cryo-EM structure of human TMEM45B with a bound GM3 (18:1;O2/24:1) pubmed.ncbi.nlm.nih.gov/42785650/ #cryoEM

Dual ATPase-activated DNA hemimethylation and cleavage by the MANTIS defence system www.biorxiv.org/content/10.64898/2026.09.23.753747v1 #cryoEM

Structural basis for differential inhibition of THIK1 by chemically related inhibitors www.biorxiv.org/content/10.64898/2026.09.21.753137v1 #cryoEM

FPGA-based scanner and SerialEM server for 4D-STEM electron tomography pubmed.ncbi.nlm.nih.gov/42775650/ #cryoEM

Temporal Dynamics of Urinary Extracellular Vesicle Excretion and Cargo in Healthy Subjects over 24 Hours pubmed.ncbi.nlm.nih.gov/42775544/ #cryoEM

The lower γ region supports forward rotation in the latter half of the 80° substep of F1-ATPase pubmed.ncbi.nlm.nih.gov/42775674/ #cryoEM

Structural mechanisms of SAMD9 autoinhibition and pathogenic dysregulation pubmed.ncbi.nlm.nih.gov/42777028/ #cryoEM

Acoustofluidic cryo-EM enables in situ particle manipulation for uniform, high-quality cryo-EM specimens pubmed.ncbi.nlm.nih.gov/42777058/ #cryoEM

Mechanism of GPR84 allosteric modulation at a helix 8-proximate site pubmed.ncbi.nlm.nih.gov/42777063/ #cryoEM

SCRIB inhibits PP1 phosphatase activity without blocking or structurally altering its active site pubmed.ncbi.nlm.nih.gov/42778107/ #cryoEM

🇨🇦 Today we kicked off our hands-on workshop, “Beyond Consensus Refinements: Advanced Cryo-EM Data Processing with CryoSPARC,” in collaboration with The Hospital for Sick Children @sickkidsto.bsky.social!

Excited for two days of diving deeper into advanced #cryoEM data processing with #CryoSPARC. 🔬

Novel human neutralizing monoclonal antibodies against Pregnancy-Associated Plasma Protein A for the treatment of Autosomal Dominant Polycystic Kidney Disease pubmed.ncbi.nlm.nih.gov/42778146/ #cryoEM

Scaffold engineering enables high-resolution cryo-EM analysis of thiamine pyrophosphate riboswitch architecture and dynamics pubmed.ncbi.nlm.nih.gov/42778278/ #cryoEM

Host membrane cholesterol constrains constitutive signaling of the oncogenic KSHV GPCR ORF74 www.biorxiv.org/content/10.64898/2026.09.22.753489v1 #cryoEM

Here you can see a cryoEM structure of the Methanosarcina mazei topoisomerase VI-minicircle DNA complex (PDB code: 9O7O)

Rendering by Francisco J. Enguita made with #ProteinImager

#SciArt #molecularart #topoisomerase #dna #minicircle #methanosarcina #cryoem

Structural Adaptability in HIV-2 Vif Drives Broad Antagonism of APOBEC3G www.biorxiv.org/content/10.64898/2026.09.21.753272v1 #cryoEM

🛑 The 𝗿𝗲𝗴𝗶𝘀𝘁𝗿𝗮𝘁𝗶𝗼𝗻 𝗱𝗲𝗮𝗱𝗹𝗶𝗻𝗲 for our #workshop in Athens, Greece is tomorrow, 𝗙𝗿𝗶𝗱𝗮𝘆 𝟮𝟱𝘁𝗵 𝗦𝗲𝗽𝘁𝗲𝗺𝗯𝗲𝗿

Don't miss out and register➡️ bioexcel.eu/a9nq

@ezgikaraca.bsky.social
#ComputerSimulation #moleculardynamics #integrativemodelling #workflows #CryoEM

FAST-MaP: Chemical Mapping of RNA Structures Using Primer-less Sequencing www.biorxiv.org/content/10.64898/2026.09.22.753544v1 #cryoEM

Kinesins as dynamic drug targets: structural insights and emerging therapeutic strategies pubmed.ncbi.nlm.nih.gov/42773013/ #cryoEM