​Which in vitro model best reflects human disease? We compared scRNA-seq profiles of >150K PBMCs across 11 stimuli, mapping them against inflammatory diseases like SLE to highlight the most clinically relevant models. Free data: doi.org/10.1186/s130... 🧪🧬🖥️ #immunosky #scRNAseq #SingleCell

¿Qué es la tecnología Single Cell? 🧬 El Dr. José Miguel Álvarez, director de PhytoLearning, te explica esta herramienta clave para entender cómo actúan los genes en una sola célula y su impacto en múltiples enfermedades.

#workshop #singlecell #phyto #ciencia #mesdelaciencia

A cellular atlas of Astyanax mexicanus embryogenesis reveals principles of developmental microevolution #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.10.07.757402v1

Pdk1-dependent metabolic heterogeneity promotes aggressive colorectal cancer through cell-intrinsic interferon signaling #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.10.07.757309v1

Tumour-stroma signaling drives a reversible program with neural-like features in cancer-associated fibroblasts #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.10.07.757165v1

Spatiotemporal Mapping of Glomerular Endothelial Regeneration Identifies Apold1 as an Intrinsic Regulator of Repair #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.10.08.757579v1

Single-nucleus multi-omics reveals reversible molecular signatures in skeletal muscle of patients with heart failure with preserved ejection fraction #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.10.07.756854v1

A minimally modified AAV9 variant (AAV9fyhr) for enhanced CNS gene delivery by intra-CSF administration. #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.10.07.756773v1

Multi-Omic and Spatial Profiling Defines Outcome-Associated Tumor States in Head and Neck Adenoid Cystic Carcinoma #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.10.07.757413v1

Epigenetics Preprint – Single-Nucleus Multi-Omic Atlas Maps Regulatory Architecture and Non-Coding Variant Effects across Adult Human Tissues www.biorxiv.org/content/10.6...

#Epigenetic #Preprint #SingleCell #MultiOmic
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Perfect for cancer, immunology, and aging research; epigenometech.com

Patient-Specific Ipsc Model for Tbx5 Reveals Transcriptomic and Metabolic Disturbances Causing Holt–Oram Syndrome #SingleCell 🧪🧬🖥️
https://www.researchsquare.com/article/rs-11267708/latest

Profiling Transcriptomic Changes Across Frontal Cortical Subregions in Major Depressive Disorder #SingleCell 🧪🧬🖥️
https://www.researchsquare.com/article/rs-7349413/latest

Dual HER2 and TROP2 Antibody–Drug Conjugates Overcome Tumor Heterogeneity in Breast Cancer #SingleCell 🧪🧬🖥️
https://www.researchsquare.com/article/rs-11269990/latest

Molecular Mechanism of Psilocybin-Induced Longevity: The c-Fos–SIRT6 Epigenetic Axis #SingleCell 🧪🧬🖥️
https://www.researchsquare.com/article/rs-11286939/latest

Age-associated transcriptional programs in tumor-associated macrophages are associated with tumor progression in HPV-negative oral cancer #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.10.02.756061v1

drugMR: A multi-omics pipeline for genetically anchored drug-target discovery #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.10.01.756031v1

Dietary magnesium supplement enhances memory through Hippo signaling #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.10.02.756214v1

Retrieval-Augmented Generation for Predicting Cellular Responses to Gene Perturbation #SingleCell 🧪🧬🖥️
https://arxiv.org/abs/2603.07233

Efficient and Generalizable Archetypal Analysis for Discrete Data #SingleCell 🧪🧬🖥️
https://arxiv.org/abs/2610.12035

A posteriori error estimation for coarse or distorted meshes #SingleCell 🧪🧬🖥️
https://arxiv.org/abs/2610.12088