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@sigtrans-sttt.bsky.socialSep 16, 2026, 3:00 AM

BCL9 drives the MerTK–ERK–SPP1 macrophage M2 program in #PulmonaryFibrosis, while its inhibition reprograms macrophage–fibroblast crosstalk toward fibroblast #Lipogenesis, supports AT2 cell expansion and attenuates #Fibrosis.

#STTT #OpenAccess: doi.org/10.1038/s413...

BCL9 inhibition promotes fibroblast lipogenesis by regulating macrophage–fibroblast interactions to attenuate pulmonary fibrosis
@4040rec.bsky.socialSep 14, 2026, 8:11 AM

#Hepatology #GileadSciences #Gilead #Livdelzi #seladelpar #Scotland #PBC #primarybiliarycholangitis #Pruritus #UDCA #NHSScotland #SMC #ScottishMedicinesConsortium #chronicitch #rarediseases #liverdisease #fibrosis #cirrhosis #liverfailure #PBCFoundation #RESPONSE #phase3
zurl.co/OHgLy

@neildufton.bsky.socialSep 10, 2026, 5:05 PM

Exciting news! My group’s new in press preview is in @insight.jci.org insight.jci.org/articles/vie.... Detailed analysis of endothelial plasticity and characteristation of fibrosis-associated EC (FAEC) phenotypes in healthy tissue, models of liver fibrosis and MSALD patients. #EndMT #fibrosis

@dgfi-org.bsky.socialSep 9, 2026, 12:05 PM

😀 We are pleased to welcome our speakers for the Main Session “Immunity in the Intestine”. www.immunology-conference.de

@efis-immunology.bsky.social @iuis-online.bsky.social @dgfi-yi.bsky.social

#immunology26 #dgfi #ImmunityInTheIntestine #Microbiome #Fibrosis #Inflammation #Immunology

Main Sessions: Immunity in the Intestine
Matthias Friedrich
Fibroblast response in intestinal inflammation and fibrosis
https://www.immunology-conference.de
#immunology26
Main Sessions: Immunity in the Intestine

Emma Wetter Slack
Using oral vaccines to manipulate microbial ecology in the gut
https://www.immunology-conference.de
#immunology26
Main Sessions: Immunity in the Intestine

Petra Bacher
T cell mediated immunity to fungal microbes in inflammatory bowel diseases
https://www.immunology-conference.de
#immunology26
Main Sessions: Immunity in the Intestine

Jakob Zimmermann
Induction, persistence, and function of microbiota-specific CD4 T cell memory
https://www.immunology-conference.de
#immunology26
@jci.orgSep 9, 2026, 1:57 AM

Commentary: An NFATC4 phospho-switch links matrix stiffness to fibroblast fate: doi.org/10.1172/JCI2...

Rebecca Shelley Frabotta & Purushothama Rao Tata @dukemedschool.bsky.social discuss Kadri et al.: doi.org/10.1172/JCI1...
#Fibrosis

@gmj-georgia.bsky.socialSep 6, 2026, 4:41 AM

Breaking: Semaglutide (Wegovy) becomes the first GLP-1 receptor agonist approved to treat metabolic dysfunction-associated steatohepatitis (MASH) with moderate-to-a… #Drugapproval #Fibrosis #GLP1agonists #Hepatology #Liverdisease #Drugapproval #Fibrosis #GLP1agonists #Hepatology #Liverdisease …