Although highest shortly after treatment initiation, the risk [of #ketoacidosis with #SGLT2 inhibitors] persists over time and should be evaluated throughout treatment. Patients should be instructed to pause treatment during acute illness and stress thelancet.com/journals/lan...
#T2D #DKA

#EndoSky

Incidental #adrenal #tumours are uncommon in adults younger than 40 years but increase in frequency with age—the highest incidence occurs in the seventh and eighth decades of life www.thelancet.com/journals/lan...
#MedSky #EndoSky

Major transformations in #lipid #metabolism & #cardiovascular disease prevention have occurred during the first quarter of the 21st century & have impacted clinical practice. Find out more in this TimeCapsule article www.thelancet.com/journals/lan...
#LDL #cholesterol

#MedSky #EndoSky #CardioSky

🧪 🩺 #MedSky @medsky.social Endocrinology #Endosky

Published in @eclinicalmed.bsky.social

The lancet commission definition of #clinical #obesity: a multi-cohort cross-sectional analysis from early childhood to older age in seven high-income countries www.thelancet.com/journals/ecl...
#OpenAccess

#MedSky #EndoSky

#MentalHealth problems can impair self-care behaviours & contribute to the development of some types of #diabetes & diabetes complications www.thelancet.com/journals/lan... #T1D #T2D #GDM
fear of #hypoglycaemia
diabetes #distress
#depression
disordered #eating
#sleep disorders

#MedSky #EndoSky

Emerging diagnostic technologies, including targeted genetic testing, #parathyroid autoimmunity assays, and point-of-care calcium monitoring, could enable individualised & real-time management of #hypoparathyroidism thelancet.com/journals/lan...
#PTH #hypocalcaemia #hyperphosphataemia

#EndoSky

Over the past two or three decades, the demographics of type 1 #diabetes have shifted to include a greater proportion of older adults, reflecting a population comprising both individuals with youth-onset and adult-onset disease www.thelancet.com/journals/lan...
#T1D #olderadults

#MedSky #EndoSky

Published in @lancetrh-americ.bsky.social

Low energy diet plus supervised exercise vs usual care alone in people with early-onset type 2 diabetes (RESET for Remission): a randomised, open-label, blinded-endpoint efficacy trial www.thelancet.com/journals/lan...
#T2D
#OpenAccess

#MedSky #EndoSky

This framework aims to support outcome selection, consistency across trials, comparison of interventions, and evaluation of disease-modifying strategies in type 2 #diabetes thelancet.com/journals/lan...
#T2D #disease #modification #outcomes

#MedSky #EndoSky

Reducing #cardiovascular morbidity and mortality and improving #HRT to ensure that all individuals with Turner syndrome are optimally treated with appropriate induction of #puberty and throughout adulthood is especially important thelancet.com/journals/lan...
#Turner syndrome

#MedSky #EndoSky

Also read the Linked Comment:
#IL-2 and immunoregulatory therapies in newly diagnosed type 1 #diabetes www.thelancet.com/journals/lan...
#T1D

#MedSky #EndoSky

Despite robust #Treg expansion confirming target engagement, low-dose #IL-2 did not preserve β-cell function in people with newly diagnosed type 1 #diabetes www.thelancet.com/journals/lan...
#T1D

#MedSky #EndoSky

Le prochain balado de BaladoCritique : club de lecture médical, portera sur l'essai clinique STAREE, publié dans le
@nejm.org, sur le traitement par statine des sujets âgés.
Enregistrement à venir le 26 octobre prochain.
À suivre !
#MedSky #EndoSky #EBM

Definition and diagnostic criteria of #clinical #obesity thelancet.com/journals/lan...
#BMI #obesity
#EASD2026

#MedSky #EndoSky

Despite strong evidence that early detection and continuous management reduce morbidity and mortality, many health systems face persistent gaps in diagnosis, treatment, and follow-up of people with diabetes www.thelancet.com/journals/lan...
#diabetes #primary #care
#EASD2026

#MedSky #EndoSky

S Alice Longa & Cate Speake comment on:
#IL-2 and immunoregulatory therapies in newly diagnosed type 1 #diabetes thelancet.com/journals/lan...
#T1D
#EASD2026

#MedSky #EndoSky

New—Efficacy and safety of low-dose #IL-2 in people with newly diagnosed type 1 #diabetes (DIABIL-2): a double-blind, multicentre, randomised, placebo-controlled, phase 2b trial thelancet.com/journals/lan...
#T1D
#EASD2026

#MedSky #EndoSky

“Atorvastatin, Cardiovascular Events, and Disability-free Survival in Older Adults.”
Publié ce jour dans le @nejm.org.
#MedSky #EndoSky
www.nejm.org/doi/full/10....

New—Diabetes and the role of primary care: a global perspective thelancet.com/journals/lan...
#diabetes
#EASD2026

#MedSky #EndoSky