Semaglutide Reduces Odorant-Driven Chemotaxis and Reproductive Output in Caenorhabditis elegans #micropublication #biology #data #caltechlibrary #Celegans #UndergraduateResearchExperience #PhenotypeDa https://micropublication.org/journals/biology/micropub-biology-002168

Cationic amphiphilic drugs (CADs) can disrupt lysosomal function. Peter Roy &co show that a xenobiotic module couples CYP-35B–mediated CAD catabolism to efflux in #Celegans, possibly to #detoxify natural products generated by microbes in the soil 🧪 buff.ly/4BFpg7V

Tags Attached to the Centrosomal Protein SPD-5 Can Disrupt Centrosome Flattening During Anaphase of the 1-cell C. elegans Embryo #micropublication #biology #data #caltechlibrary #Celegans #Other #Meth https://micropublication.org/journals/biology/micropub-biology-002285

An F2A sequence permits correct localization of a secreted and a nuclear localized reporter in C. elegans #micropublication #biology #data #caltechlibrary #Celegans #Methods #Methodology #NewFinding https://micropublication.org/journals/biology/micropub-biology-002351

🪱 A new #Omics report in #G3journal identifies the complex interplay between the heat shock response and the unfolded protein response of the ER in #Celegans, emphasizing the existence of both compartment-specific and shared regulatory mechanisms.

🔗 buff.ly/ObdgHLf

An ultra-rapid mounting method for C. elegans embryos that enables long-term, multi-sample live imaging #micropublication #biology #data #caltechlibrary #Celegans #Methods #Methodology https://micropublication.org/journals/biology/micropub-biology-002361

A commercially available DJ-1 antibody does not detect C. elegans DJR-1.1 or DJR-1.2 proteins in whole worm lysates #micropublication #biology #data #caltechlibrary #Celegans #ExpressionData #Negative https://micropublication.org/journals/biology/micropub-biology-002375

High confidence HIF-1 target genes for quantifying the activation of the HIF-1-mediated hypoxia response #micropublication #biology #data #caltechlibrary #Celegans #ExpressionData #Methods #NewFinding https://micropublication.org/journals/biology/micropub-biology-002304

🐛 Ayer arrancó en Valencia el X Spanish Worm Meeting, reuniendo a la comunidad que investiga con C. elegans.

🏅 Una jornada que cerró con la plenaria de Victor R. Ambros, Nobel de Medicina 2024.

📍Una edición muy especial que devolvió el evento al lugar donde todo empezó en 2007.

#IBVCSIC #celegans

Caenorhabditis Intervention Testing Program: the putative mTOR inhibitors Cinnarizine and Meclizine do not extend lifespan in C. elegans #micropublication #biology #data #caltechlibrary #Celegans #Phe https://micropublication.org/journals/biology/micropub-biology-002198

Friday vibes, #Celegans style. 🪱

We’re not saying our scientists have a favorite model organism… but someone on campus decided to share their love of nematodes with the world. 🧪🔬

Science meets art at MDI Bio Lab. We approve.

🪱 New in #GENETICS: Single-molecule FISH data reveal mRNA distributions of key Wnt pathway components during L2 symmetric and asymmetric seam cell divisions in #Celegans, uncovering a transcriptional feedback that may reinforce robust fate specification.

🔗 buff.ly/8sUcXYL

Chromosome-Scale Assembly of Novel Caenorhabditis sp. 61 (strain JU4110) #micropublication #biology #data #caltechlibrary #Celegans #GenomeAnnouncements #NewFinding https://micropublication.org/journals/biology/micropub-biology-002358

📈 #TrendingWithImpact:
"Disruption of the insulin/IGF-1 signaling pathway in Caenorhabditis elegans dramatically increases male longevity and enhances reproductive health late in life"

#PressRelease ⬇️
https://bit.ly/3UKG0qj

#Aging #Longevity #Healthspan #Lifespan #Celegans

🪱 In #GENETICS, @siegfriedhekimi.bsky.social & Co identify acclimation stress as a novel type of cellular stress in #Celegans, where frequent fluctuations between physiological temperatures severely impair the short-term survival of worms.

🔗 buff.ly/4FVSYej

🪱 A behavior analysis in #Celegans highlights that the change in reproductive strategies to increase mating following dauer diapause requires sexually dimorphic changes in behavior.

Find out more in #G3journal 🔗 buff.ly/Zgi3QXQ

📢 Read the Published Paper!

👉 Development and Multi-Level Characterization of Cocoa-Flavored Tiger Nut Beverages (Horchata): From Physicochemical and Sensory Properties to In Vivo Antioxidant Assessment
📍https://www.mdpi.com/2306-5710/12/8/94

#MDPI #beverages #functionalfood #Celegans #consumer

🪱 In #GENETICS, Sophia Villiere and @michaelphart1.bsky.social identify rig-6/contactin as a temporally restricted regulator of GABAergic neuron remodeling in #Celegans, acting cell-autonomously to promote neurite outgrowth during the L4-to-adult transition.

🔗 buff.ly/8430n1J

🪱 A new study in #G3journal describes the importance of RRC-1's lipid interactions at the cell membrane for the proper assembly and function of Integrin adhesion complexes in #Celegans muscles.

🔗 buff.ly/82d9DXn

#Celegans is advancing #VirusHostInteraction research.

From #Antiviral #RNAi & #InnateImmune responses to #ReverseGenetics for Orsay virus, #nematodes provide a simple yet powerful model. #medsky

Read: doi.org/10.1007/s115...

#currentmedicalscience #Virology #ModelOrganisms