@currentmedscience.bsky.social#Bcl2 family proteins regulate cell survival and death, with roles spanning autophagy, calcium #homeostasis, and mitochondrial dynamics, offering therapeutic promise through BH3 mimetics. #medsky
To read: doi.org/10.1007/s115...
@currentmedscience.bsky.socialCan #Microglia hold the key to stroke defense?
Casr-related neuroprotection induced by ischemic preconditioning is linked to M2 microglial transformation, offering insight into #IschemicStroke defense. #medsky
Read: doi.org/10.1007/s115...
@currentmedscience.bsky.socialFindings show #PPA1 interacts with FUS to prevent mitochondrial mislocalization, preserving mitochondrial function & promoting adipose browning, highlighting its therapeutic potential in #MetabolicDisorders. #medsky
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#currentmedicalscience #Metabolism
@currentmedscience.bsky.social#UTROSCTs: rare uterine tumors with uncertain malignant potential. This study combines a literature review and 8 cases revealing novel markers and long term disease free outcomes. #medsky
Full article: doi.org/10.1007/s115...
@currentmedscience.bsky.socialHow does konjac oligosaccharide (KOS) improve gut motility?
By activating the 5 HT4R/cAMP/PKA/p CREB pathway, KOS improves loperamide-induced #constipation, enhancing #IntestinalMotility. #medsky
Read here: doi.org/10.1007/s115...
@currentmedscience.bsky.social#Epigenetics offers new hope for #SNHL.
This review explores #histone modifications, #DNAMethylation & ncRNAs in hair cell damage, highlighting small‑molecule compounds as promising therapies for SNHL. #medsky
To read: doi.org/10.1007/s115...
@currentmedscience.bsky.social#WorldHeartDay | September 29, 2026
#CardiovascularDisease remains a research priority, advancing prevention, early diagnosis, and #TranslationalMedicine.
#CurrentMedicalScience publishes peer-reviewed #cardiovascularresearch and clinical innovation.
Explore recent articles: t.co/5LdKznXcNc
@currentmedscience.bsky.socialThis study reveals that #Electroacupuncture activates GDNF/GFRα1/PI3K/Akt signaling, increases enteric glial cells, and improves gastrointestinal motility in #FunctionalDyspepsia. #medsky
To read: doi.org/10.1007/s115...
@currentmedscience.bsky.social#mRNAVaccines hold promise in #Oncology.
This review highlights RNA design, lipid nanoparticle delivery, antigen encoding, and immunomodulators as strategies to overcome TME barriers in cancer #immunotherapy. #medsky
To read: doi.org/10.1007/s115...
@currentmedscience.bsky.socialBy analyzing #CD8+, CD4+, NKT, and γδ T cells, this study underscores the promise of TCR‑T, #CART, and checkpoint inhibitors in achieving long‑term AML control and advancing future therapeutic strategies. #medsky
To read: doi.org/10.1007/s115...
@currentmedscience.bsky.socialStudy links decreased Akkermansia with higher inflammatory risk in unstable angina, pointing to the microbiota’s role in disease & the need for mechanistic clarity. @2024_HUST
Read: doi.org/10.1007/s115...
@currentmedscience.bsky.socialThis review highlights altered tryptophan #Metabolism in #obesity, underscoring its potential as a therapeutic target for metabolic and psychological comorbidities. #medsky
Know more: doi.org/10.1007/s115...
@currentmedscience.bsky.socialReciprocal activation between S100A9 and TLR2 amplifies hypertrophic signaling in mechanically stretched #cardiomyocytes, exacerbating maladaptive remodeling and likely accelerating HF progression, highlighting therapeutic targets. #medsky
To read: doi.org/10.1007/s115...
@currentmedscience.bsky.socialThe global burden of PAH is rising unevenly, with high SDI regions seeing more cases. The study calls for equitable resources and better diagnostics. #medsky
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#currentmedicalscience #Cardiology #HealthEquity #GlobalHealth
@currentmedscience.bsky.socialCombination therapy shows promise in #schistosomiasis care.
YCHD and PZQ reduce #granulomatous inflammation and #fibrosis by inhibiting apoptosis and ER stress, offering therapeutic promise. #medsky
To read: doi.org/10.1007/s115...
#currentmedicalscience #Hepatology
@currentmedscience.bsky.socialThe #MUFA content of #Avocado oil varies by cultivar.
This study highlights metabolic promise but calls for standardization of therapeutic applications across cultivars. #medsky
To read: doi.org/10.1007/s115...
@currentmedscience.bsky.socialThis study demonstrates that #CHOP deficiency intensifies inflammation, epithelial #apoptosis, and injury in OAB mice by suppressing #ERStress, pointing to CHOP as a therapeutic axis. #medsky
Read more: doi.org/10.1007/s115...
@currentmedscience.bsky.socialThis study summarizes the role of #TranscriptionFactors in #ALD pathology—from lipid metabolism to ER stress—and highlights promising targeted therapies for ALD treatment. #medsky
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@currentmedscience.bsky.socialSIC raises mortality; pre‑SIC increases risk.
A #nomogram-based prediction model enables early SIC identification, improving #sepsis management & outcomes. #medsky
Read more: doi.org/10.1007/s115...
@currentmedscience.bsky.socialCan a natural compound protect the #Liver from alcohol induced iron overload?
This study reveals that #quercetin sustains ferritinophagic flux & lysosomal function via #FOXO1 TFEB NCOA4 signaling. #medsky
To read: doi.org/10.1007/s115...
