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@plosbiology.orgSep 24, 2026, 12:55 PM

Cationic amphiphilic drugs (CADs) can disrupt lysosomal function. Peter Roy &co show that a xenobiotic module couples CYP-35B–mediated CAD catabolism to efflux in #Celegans, possibly to #detoxify natural products generated by microbes in the soil 🧪 buff.ly/4BFpg7V

Working model of the CAD Defense Pathway. CAD metabolites and polar lipids are exported by PGP‑13 and PGP‑14 across the plasma membrane; CAD also signals (directly or indirectly) to nuclear receptors (NHRs) to activate cyp‑35b, cror‑1 and pgp‑13, forming a feedback loop.
@micropub7n.bsky.socialSep 24, 2026, 4:59 AM

Purine salvage enzymes are innate immune regulators in Caenorhabditis briggsae and Caenorhabditis remanei #micropublication #biology #data #caltechlibrary #Celegans #Caenorhabditisbriggsae #Caenorhabd https://micropublication.org/journals/biology/micropub-biology-002371

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@genetics-gsa.bsky.socialSep 23, 2026, 6:02 PM

🪱 Using a CRISPR-based, cell-specific degradation approach, Amezquita et al. demonstrate that the Integrin-Talin axis functions cell-autonomously in #Celegans mechanosensory neurons to regulate presynaptic branch formation.

📖 more in #G3journal 🔗 buff.ly/328B9hw

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@micropub7n.bsky.socialSep 23, 2026, 4:01 PM

Semaglutide Reduces Odorant-Driven Chemotaxis and Reproductive Output in Caenorhabditis elegans #micropublication #biology #data #caltechlibrary #Celegans #UndergraduateResearchExperience #PhenotypeDa https://micropublication.org/journals/biology/micropub-biology-002168

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@plosbiology.orgSep 23, 2026, 8:00 AM

Cationic amphiphilic drugs (CADs) can disrupt lysosomal function. Peter Roy &co show that a xenobiotic module couples CYP-35B–mediated CAD catabolism to efflux in #Celegans, possibly to #detoxify natural products generated by microbes in the soil 🧪 buff.ly/4BFpg7V

Working model of the CAD Defense Pathway. CAD metabolites and polar lipids are exported by PGP‑13 and PGP‑14 across the plasma membrane; CAD also signals (directly or indirectly) to nuclear receptors (NHRs) to activate cyp‑35b, cror‑1 and pgp‑13, forming a feedback loop.
@micropub7n.bsky.socialSep 23, 2026, 4:30 AM

Tags Attached to the Centrosomal Protein SPD-5 Can Disrupt Centrosome Flattening During Anaphase of the 1-cell C. elegans Embryo #micropublication #biology #data #caltechlibrary #Celegans #Other #Meth https://micropublication.org/journals/biology/micropub-biology-002285

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@micropub7n.bsky.socialSep 21, 2026, 7:38 PM

An F2A sequence permits correct localization of a secreted and a nuclear localized reporter in C. elegans #micropublication #biology #data #caltechlibrary #Celegans #Methods #Methodology #NewFinding https://micropublication.org/journals/biology/micropub-biology-002351

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@genetics-gsa.bsky.socialSep 21, 2026, 4:04 PM

🪱 A new #Omics report in #G3journal identifies the complex interplay between the heat shock response and the unfolded protein response of the ER in #Celegans, emphasizing the existence of both compartment-specific and shared regulatory mechanisms.

🔗 buff.ly/ObdgHLf

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@micropub7n.bsky.socialSep 17, 2026, 6:50 PM

An ultra-rapid mounting method for C. elegans embryos that enables long-term, multi-sample live imaging #micropublication #biology #data #caltechlibrary #Celegans #Methods #Methodology https://micropublication.org/journals/biology/micropub-biology-002361

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@micropub7n.bsky.socialSep 15, 2026, 9:14 PM

A commercially available DJ-1 antibody does not detect C. elegans DJR-1.1 or DJR-1.2 proteins in whole worm lysates #micropublication #biology #data #caltechlibrary #Celegans #ExpressionData #Negative https://micropublication.org/journals/biology/micropub-biology-002375

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@micropub7n.bsky.socialSep 15, 2026, 7:04 PM

High confidence HIF-1 target genes for quantifying the activation of the HIF-1-mediated hypoxia response #micropublication #biology #data #caltechlibrary #Celegans #ExpressionData #Methods #NewFinding https://micropublication.org/journals/biology/micropub-biology-002304

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@ibv-csic.bsky.socialSep 15, 2026, 8:04 AM

🐛 Ayer arrancó en Valencia el X Spanish Worm Meeting, reuniendo a la comunidad que investiga con C. elegans.

🏅 Una jornada que cerró con la plenaria de Victor R. Ambros, Nobel de Medicina 2024.

📍Una edición muy especial que devolvió el evento al lugar donde todo empezó en 2007.

#IBVCSIC #celegans

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@micropub7n.bsky.socialSep 14, 2026, 4:01 AM

Caenorhabditis Intervention Testing Program: the putative mTOR inhibitors Cinnarizine and Meclizine do not extend lifespan in C. elegans #micropublication #biology #data #caltechlibrary #Celegans #Phe https://micropublication.org/journals/biology/micropub-biology-002198

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@mdibl.orgSep 11, 2026, 3:00 PM

Friday vibes, #Celegans style. 🪱

We’re not saying our scientists have a favorite model organism… but someone on campus decided to share their love of nematodes with the world. 🧪🔬

Science meets art at MDI Bio Lab. We approve.

a drawing on a blackboard of a worm
@genetics-gsa.bsky.socialSep 11, 2026, 1:03 PM

🪱 New in #GENETICS: Single-molecule FISH data reveal mRNA distributions of key Wnt pathway components during L2 symmetric and asymmetric seam cell divisions in #Celegans, uncovering a transcriptional feedback that may reinforce robust fate specification.

🔗 buff.ly/8sUcXYL

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@micropub7n.bsky.socialSep 11, 2026, 5:00 AM

Chromosome-Scale Assembly of Novel Caenorhabditis sp. 61 (strain JU4110) #micropublication #biology #data #caltechlibrary #Celegans #GenomeAnnouncements #NewFinding https://micropublication.org/journals/biology/micropub-biology-002358

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@aging-us.bsky.socialSep 10, 2026, 4:00 PM

📈 #TrendingWithImpact:
"Disruption of the insulin/IGF-1 signaling pathway in Caenorhabditis elegans dramatically increases male longevity and enhances reproductive health late in life"

#PressRelease ⬇️
https://bit.ly/3UKG0qj

#Aging #Longevity #Healthspan #Lifespan #Celegans

@genetics-gsa.bsky.socialSep 9, 2026, 1:03 PM

🪱 In #GENETICS, @siegfriedhekimi.bsky.social & Co identify acclimation stress as a novel type of cellular stress in #Celegans, where frequent fluctuations between physiological temperatures severely impair the short-term survival of worms.

🔗 buff.ly/4FVSYej

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@genetics-gsa.bsky.socialSep 8, 2026, 8:01 PM

🪱 A behavior analysis in #Celegans highlights that the change in reproductive strategies to increase mating following dauer diapause requires sexually dimorphic changes in behavior.

Find out more in #G3journal 🔗 buff.ly/Zgi3QXQ

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@beveragesmdpi.bsky.socialSep 8, 2026, 8:56 AM

📢 Read the Published Paper!

👉 Development and Multi-Level Characterization of Cocoa-Flavored Tiger Nut Beverages (Horchata): From Physicochemical and Sensory Properties to In Vivo Antioxidant Assessment
📍https://www.mdpi.com/2306-5710/12/8/94

#MDPI #beverages #functionalfood #Celegans #consumer