Structure-based analysis reveals a hydrophobic pocket governing P2Y12 receptor agonist potency and selectivity pubmed.ncbi.nlm.nih.gov/42786908/ #cryoEM

Structural biology of the TRPM4 channel: architecture, modulation, and therapeutic opportunities pubmed.ncbi.nlm.nih.gov/42787536/ #cryoEM

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure-function relationships and relevance to human pathology pubmed.ncbi.nlm.nih.gov/42788437/ #cryoEM

Chaperoning by dynamic encasement: Structural basis of linker histone H1 nuclear import pubmed.ncbi.nlm.nih.gov/42790418/ #cryoEM

In-cell structures visualize human pre-ribosome assembly in the nucleolus pubmed.ncbi.nlm.nih.gov/42784657/ #cryoEM

Interested in #cryoEM and #GPCRs? 🤔
Our review 'Tools to investigate class B1 GPCR conformational landscapes with cryo-EM and beyond' was recently published and our image selected as issue cover in Biochem Society Transactions!🤩 👇
doi.org/10.1042/BST2...

Rendered using Blender #MolecularNodes👏

Electron microscopy reveals water networks inside hydrated cellulose fibers pubmed.ncbi.nlm.nih.gov/42779753/ #cryoEM

Structural basis of diverse antibody recognition of conserved coronavirus spike S2 epitopes that contribute to protective immunity pubmed.ncbi.nlm.nih.gov/42779668/ #cryoEM

The CAHRA Challenge: A Community-Wide Assessment of Cryo-EM Heterogeneous Reconstruction Algorithms pubmed.ncbi.nlm.nih.gov/42779743/ #cryoEM

Structural Basis for MCAM Mediated Inhibition of Laminin Dependent Cell Migration pubmed.ncbi.nlm.nih.gov/42779840/ #cryoEM

Structural and biophysical insights into the unique RNase YicC pubmed.ncbi.nlm.nih.gov/42779889/ #cryoEM

Cryo-EM Structures of Infectious Low-Twist α-Synuclein Filaments in Lewy Bodies pubmed.ncbi.nlm.nih.gov/42780058/ #cryoEM

A 3D Soft X-Ray Structural Atlas of Multicellular Cable Bacteria pubmed.ncbi.nlm.nih.gov/42780080/ #cryoEM

Structural heterogeneity of CTE Type I tau filaments with an interface-shifted polymorph pubmed.ncbi.nlm.nih.gov/42780235/ #cryoEM

Distinct structural mechanisms drive gain-of-function activation of TMEM16E in gnathodiaphyseal dysplasia pubmed.ncbi.nlm.nih.gov/42780283/ #cryoEM

Chimeric SARS-CoV-2 vaccine vectors stably incorporating the functional glycoprotein of VSV pubmed.ncbi.nlm.nih.gov/42781491/ #cryoEM

In situ visualization of autophagy reveals the presence of vesicles at the expanding phagophore rim pubmed.ncbi.nlm.nih.gov/42781864/ #cryoEM

On-grid enrichment strategies in cryo-EM: affinity-functionalized supports for low-abundance and challenging targets pubmed.ncbi.nlm.nih.gov/42781870/ #cryoEM

High-resolution cryoEM of nucleosomes in nuclear extracts of mammalian cells pubmed.ncbi.nlm.nih.gov/42782067/ #cryoEM

Multilevel Mechanisms by Which Membrane Transport Proteins Regulate Plant Responses to Heavy Metal Stress: From Ion Perception and Uptake Control to Systemic Signaling and Translational Perspectives pubmed.ncbi.nlm.nih.gov/42782210/ #cryoEM