#Umma is playing now in the #ChronicLoaf stream
#Criptober #Mutation #spookyseason #scarymovies #FilmFriday #disability #longcovid #autism #insomnia #mecfs
@chronicloaf.bsky.social
@chronicloaf.bsky.social#Umma is playing now in the #ChronicLoaf stream
#Criptober #Mutation #spookyseason #scarymovies #FilmFriday #disability #longcovid #autism #insomnia #mecfs
@oudais.bsky.socialHHV-7 positivity was markedly higher in a small selected cohort, but historical controls and referral bias make the finding hypothesis-generating only.
@oudais.bsky.social3. Among 6,364 patients, post-infection cardiometabolic worsening was associated with 1.36-fold higher odds of Long COVID, although reverse causation remains plausible.
@oudais.bsky.socialThis does not negate neurological disease; it separates microstructural, neurovascular, and functional abnormalities from overt atrophy.
@oudais.bsky.social2. A study of 77 patients linked cognitive impairment to distributed MRI microstructural features. Conversely, a Bayesian synthesis of 21 MRI experiments found no reproducible regional volume loss.
@oudais.bsky.social1. Persistent S and N proteins were associated with vascular inflammation across human samples, cells, and mouse models after infectious virus clearance. This supports a non-replicating antigen–TLR4/NF-κB pathway, but human causality and treatment implications remain unproven.
@oudais.bsky.socialEnglish Summary
1 | Remnant viral proteins may link infection to vascular inflammation
2 | Neurological Long COVID may involve subtle changes rather than focal atrophy
3 | Cardiometabolic worsening is associated; HHV-7 remains unconfirmed
@oudais.bsky.social3｜代謝悪化は関連、HHV-7はまだ保留
6,364人の研究で感染後の心血管代謝リスク上昇はLong COVIDのオッズ1.36倍と関連したが、活動低下などの逆因果が残る。HHV-7陽性率は76.7%対29.1%だったものの、検査依頼患者と歴史的対照の比較であり追試待ち。
@oudais.bsky.social1｜残存ウイルス蛋白と血管炎症を結ぶ機序
感染性ウイルス消失後も残るS・N蛋白が、細胞・マウス・ヒト試料で血管炎症と関連した。複製ウイルス持続とは別に、残存蛋白がTLR4／NF-κBを刺激する仮説を支持するが、ヒトでの因果性と治療効果は未確定。
2｜脳症状は萎縮より微細構造・機能の問題か
Long COVID 77人では認知低下とMRI微細構造が一つの軸を形成した。一方、21件のMRI実験を統合した解析では、再現可能な局所脳容積減少はなかった。神経症状の否定ではなく、炎症・神経血管・機能異常と組織萎縮を分ける必要がある。
#コロナ
#コロナ後遺症
#Covid19
#LongCovid
@oudais.bsky.socialLong COVID研究週報：2026年9月19日〜25日
今週は、保存価値の基準を満たす資料を5件に絞りました。確証的な治療RCTはなく、機序研究2件、神経画像研究1件、メタ解析1件、代謝リスク研究1件です。
@marushka-t.bsky.socialA good reminder that you can't predict the long-term outcome of a COVID infection by the severity of symptoms (or lack of symptoms) during the acute phase.
@longcovidsignal.bsky.socialPersistent symptoms linked to lower parent-rated Chinese reading in upper grades and lower Chinese spelling in Hong Kong elementary children.
Parent ratings and test scores diverged by grade level across infection groups in this cross-sectional study. (n=195) #LongCovid
@thewhn.bsky.social(...) Taking steps to reduce COVID-19 infections remains important for protecting your long-term health.
Learn more at whn.global.
#COVID #COVID19 #LongCOVID #LongCOVIDAwareness #PublicHealth
@chronicloaf.bsky.social#TheTwin (2024) is our next horror movie in the #ChronicLoaf stream today
#Criptober #Mutation #spookyseason #scarymovies #FilmDis #autism #DisabilityCommunity #longcovid
@benking01.bsky.social7pm on Friday evening after another busy day of teaching.
FOURTEEN #VisibleHealth PacePoints behind my daily pacesetter and my heartrate rarely exceeded 100bpm all day 🤔
#LongCovid is tricksy...
@maskblocwr.bsky.social