We're thrilled to see positive results from @biovie.bsky.social's clinical trial on bezisterim in #LongCovid!

The drug benefited patients with high levels of fatigue, PEM and/or cognitive impairment, with multiple significant and trending results, including objective cognitive tests. 1/

PLRC member @julialmv.bsky.social was just featured in @smithsonianmag.bsky.social — discussing her journey as a #LongCovid patient advocate and her work with PLRC.

"The paper that collaboration yielded... has since been viewed online two million times, and it has been cited 4,000 times"

Neuromuscular dysfunction in #LongCovid shows changes between 1.2 - 2.6 yrs from infection:

Muscle disease dropped from 78% (1.2 yrs) to 18% (2.6 yrs).

But SFEMG (junction where nerve meets muscle) stayed abnormal: 54% (1.2 yrs) to 56% (2.6 yrs).

www.sciencedirect.com/science/arti...

Sex was significant: female sex = 454% more likely to have a MACE (vs 258% for male).

Variant didn't matter - risk of MACEs were 308% for Alpha, 310% for Delta, & 335% for Omicron.

Age didn't matter - risk was 363% for <65 & 283% for 65+.

link.springer.com/article/10.1... 2/ #LongCovid

Large study (av age 45) shows people with #LongCovid are 4.48x more likely to have a Major Adverse Cardiovascular Event (stroke, pulmonary embolism, heart failure) & 53% more likely to die.

True regardless of age, BMI, vaccination, variant. Risks last 3+ years from infection. 1/