@sidchop.bsky.social
Neuroscientist and psychologist interested in better treatments, brains & psychosis. Research Fellow @UniMelb @orygen_aus
@misicbata.bsky.socialReposted by @sidchop.bsky.socialSpatial organization of AQP4 water channel expression in the human brain | doi.org/10.1126/scia...
Aquaporins are a key component of the glymphatic system. How are they distributed + how do they relate to brain function and dysfunction? ⤵️
@biologicalpsych.bsky.socialReposted by @sidchop.bsky.socialIn our latest episode of The Biological Psychiatry Podcast, we sit down with Dr. @sidchop.bsky.social from @orygen.org.au and the @unimelb.edu.au to discuss his latest work distinguishing the effects of psychotic illness and antipsychotic medication on the brain.
@avramholmes.bsky.socialReposted by @sidchop.bsky.socialNew paper from former @holmeslab-bhi.bsky.social post-doc @sidchop.bsky.social. In first-episode psychosis, antipsychotic-naive patients on placebo showed widespread cortical thinning over 12mo. However, patients on antipsychotics did not. Thinning appears to be illness- not drug-driven.
@sidchop.bsky.socialthanks to a large team across Orygen, Monash, Melbourne, Yale and Rutgers Uni. @stephenwood8.bsky.social @avramholmes.bsky.social @dralexholmes.bsky.social @ashleasegal.bsky.social
@sidchop.bsky.social🧠 Excited to share the results of our placebo-controlled RCT in psychosis: cortical thinning in the first year of illness is very likely not because of antipsychotic medication, but due to the illness itself.
www.biologicalpsychiatryjournal.com/article/S000...
Thanks to @alexfornito.bsky.social &
@sidchop.bsky.social🧩New study: "Network Constraints on 𝘪𝘯 𝘷𝘪𝘷𝘰 Synaptic Alterations in Schizophrenia"
We map a prominent brain-wide pattern of synaptic defects in people with Schizophrenia using PET, then model the molecular, cellular & connectomic features shaping this pattern 🧵1/3👇
