Nils Homer (@nilshomer.com)

@nilshomer.com Oct 14, 2026, 5:10 PM

You're work definitely sets the bar, thanks for giving us a deep dive on these methods and tools!

@nilshomer.com Oct 5, 2026, 8:13 PM

bwa-mem3 is now 6-8x faster than the original, and now as fast as minibwa. What's stopping you from using it?

@nilshomer.com Sep 14, 2026, 4:08 PM

bwa-mem3 v0.12.0 is out 🧬

Since v0.10.0: faster on both Arm & x86 (--fast is now ~2× minibwa and stock is within ~15% on x86) while staying a byte-identical (--compat). It also brings ~30–40% faster methylation and a big memory-safety pass.

github.com/fg-labs/bwa-...

#bioinformatics #genomics