🗞️Our September issue is live!✨Read about trained immunity driving inflammaging; senomorphic potential of CDK4/6 inhibitors; muscle grafts mimic exercise benefits; mtDNA drives ovarian inflammation; aging diseases dominate global health & much more!
www.nature.com/nataging/vol...
Online now! Multimorbidity patterns influenced the efficacy of a multicomponent lifestyle intervention targeting mobility disability in frail older adults. Participants with psychiatric and unspecific disease patterns experienced the most consistent clinical benefits.
doi.org/10.1038/s435...
Online now! Subcutaneous transplantation of autologous myocytes forms myografts that are vascularized, contract continuously, and improve systemic muscle function, metabolic regulation, and tissue regeneration in aged and obese mouse models.
(rdcu.be/1EM9fn2qt5ra)
Also see the associated News & Views by Subhasri Biswas and Michael Stout (rdcu.be/b13jWVxa3r6a)
doi.org/10.1038/s435...
Online now! New study shows that aging oocytes leak mitochondrial DNA into the cytosol where it activates the cGAS-STING pathway, driving inflammatory signaling in oocytes as well as neighboring granulosa cells via cGAMP transfer (rdcu.be/hp98RtvYsuya)
