James Hay

@jameshay.bsky.social

Research Fellow at the Pandemic Sciences Institute, University of Oxford. Using maths and stats to understand infectious disease dynamics, mostly viral kinetics and serology. https://hay-idd.github.io/

@jameshay.bsky.social

I hope that by making serosolver and other tools increasingly accessible and flexible, we can move the field towards a more mature state on par with Rt estimation and phylodynamics! Please do check it out, and get in touch if this is something you’re interested in.

@jameshay.bsky.social

Each one of these projects required a new feature or modification to serosolver, which I’ve finally managed (with the help of my colleague Dr. Luna GPT) to bundle together into a single stable version with comprehensive documentation and vignettes.

@jameshay.bsky.social

serosolver's USP is that it's flexible enough to work for other antigenically variable pathogens (like SARS-CoV-2), using antigenic maps as input data to disentangle cross-reactive responses. However, it also accommodates pathogens/questions where we only need to consider a single antigen.

@jameshay.bsky.social

What does the package do? serosolver takes individual-level serological data to jointly estimate lifetime infection histories and antibody kinetics. We originally developed the model to analyse influenza antibody landscapes, where accounting for cross-reactivity between strains is essential.

@jameshay.bsky.social

serosolver's USP is that it's flexible enough to work for other antigenically variable pathogens (like SARS-CoV-2), using antigenic maps as input data to disentangle cross-reactive responses. However, it also accommodates pathogens/questions where we only need to consider a single antigen.

@jameshay.bsky.social

What does the package do? serosolver takes individual-level serological data to jointly estimate lifetime infection histories and antibody kinetics. We originally developed the model to analyse influenza antibody landscapes, where accounting for cross-reactivity between strains is essential.

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