@jpkbravo.bsky.social
Assistant Professor @ ISTA
Using cryo-EM to understand how bacteria defend themselves
https://bravo-lab.org/
@asantiagofrangos.bsky.socialReposted by @jpkbravo.bsky.socialOur lab's first preprint! The antiphage protein Tiamat is an ATPase and DNase with homologs across the tree of life. What started as undergrad Shirley Yuan's summer project grew into a paper and a collaboration with
@jpkbravo.bsky.social's group. Link: www.biorxiv.org/content/10.6...
@eiriklag.bsky.socialReposted by @jpkbravo.bsky.socialVery excited to share the first preprint from my PhD with the community! This is also the first paper from the Plant Immunogenomics group with @galofir.bsky.social, so stay tuned for more!
www.biorxiv.org/content/10.6...
1/n 🧵
@anthropic.extwitter.linkReposted by @jpkbravo.bsky.socialClaude has discovered a previously unknown enzyme system hidden in the DNA of bacteriophages. Beside the enzyme’s gene sits a long array of repeating DNA—a structure that looks somewhat similar to CRISPR. We don’t yet understand what this system does, but only a handful of known systems share it...
@martinpacesa.bsky.socialReposted by @jpkbravo.bsky.socialʙɪɴᴅᴄʀᴀꜰᴛ2 is out, and we're not waiting for the paper. The full code drops today, free for academic and industry use.
We're releasing it early so you can start designing right now, and bring its full power to the current Adaptyv competition.
github.com/PacesaLab/Bi...
@jpkbravo.bsky.socialReally excited to see these two important and fascinating VIPR papers out in Science! It was a real privilege to write the accompanying Perspective and explore what this remarkable system might tell us about RNA-guided immunity and the origins of CRISPR. Congratulations to the whole team! 🧬
@francoisrousset.bsky.socialReposted by @jpkbravo.bsky.social🚨 We are excited to share the first preprint of our lab !
We discovered an NADase enzymatic domain in bacterial immunity and in the human protein TEP1.
@biorxiv-microbiol.bsky.socialReposted by @jpkbravo.bsky.socialA widespread NADase domain links bacterial immunity with human TEP1 https://www.biorxiv.org/content/10.64898/2026.09.04.749371v1
@jpkbravo.bsky.social…and in other great news, our lab has also been awarded an ERC Starting Grant! 🥳 Very excited for what’s ahead and incredibly grateful to my team, collaborators, and everyone who has supported us along the way.
@jpkbravo.bsky.socialHonored to be named a 2026 Vallee Scholar! 🎉 Excited about the research ahead and especially to be part of the Vallee Scholar community.
@haselbachlab.bsky.socialReposted by @jpkbravo.bsky.socialLast call: registration for the 9th Austrian Cryo-EM (ACE) Symposium closes tomorrow, 1 September.
24-25 Sept at the IMP, Vienna BioCenter. Eight invited speakers, selected talks, poster session.
