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Charles Tapley Hoyt

@cthoyt.scholar.social.ap.brid.gy

2 Following18 Followers

Bio/cheminformatician, software developer, open scientist. πŸ‡ΊπŸ‡Έ living in Bonn πŸ‡©πŸ‡ͺπŸ‡ͺπŸ‡Ί (he/him)

Current projects: @NFDI4Chem and @dalia

πŸŒ‰ bridged from ⁂ https://scholar.social/@cthoyt, follow @ap.brid.gy to interact

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@ploum.mamot.fr.ap.brid.gyOct 14, 2026, 1:54 PMReposted by @cthoyt.scholar.social.ap.brid.gy

I’ve read today a contributor to an open source project says, in substance: "If generated code is accepted in the project, I will stop contributing because I don’t want to spend time trying to understand the code in order to contribute just to see it changed the next generated commit" […]

@dhowett.mas.to.ap.brid.gyOct 13, 2026, 5:00 PMReposted by @cthoyt.scholar.social.ap.brid.gy

When I talk about the impact of language-model-based and "agentic" coding on open-source communities, and on human to human interaction, I am more often than not talking about: - How I cannot trust there is a human on the other end who wants to learn or be part of my community - How it is an […]

@cthoyt.scholar.social.ap.brid.gyOct 12, 2026, 5:50 PM

@andrewnez then I challenge you to write a program to make revving your car's engine into music :)

@cthoyt.scholar.social.ap.brid.gyOct 12, 2026, 4:59 PM

@andrewnez are you musical? do you want to try and record some of these covers? happy to supply guitar, bass, or saxophone

@cthoyt.scholar.social.ap.brid.gyOct 9, 2026, 10:40 AM

alternate perspective, if you're from a background with high respect and position: your title isn't part of your label, that's modeled with a relationship to the kind of degree you got, when, and by whom it was conferred

@cthoyt.scholar.social.ap.brid.gyOct 9, 2026, 10:35 AM

one minor way I try and promote early career researchers in academia is to always remove titles (e.g., Dr. and Prof.) from senior researchers in written text

-> currently building the @NFDI bibliometric knowledge graphs for NFDI Section International Engagaement

@cthoyt.scholar.social.ap.brid.gyOct 5, 2026, 6:39 PM

@egonw @bioregistry does the linkml handle render for you alright? fosstodon is blocked on scholar.social

@cthoyt.scholar.social.ap.brid.gyOct 5, 2026, 2:20 PM

just submitted an abstract to present @bioregistry at the @[email protected] 2026 Virtual LinkML Community Symposium

the proposed talk is about the `bioregistry validate linkml` command, which can help LinkML modelers to choose standard prefixes for their CURIEs and URIs

it'll expand on […]

@cthoyt.scholar.social.ap.brid.gySep 22, 2026, 10:10 AM

@biohackrxiv sounds great, will read soon! building a more sustainable foundation than pandoc would be a key step towards this. My experience contributing to pandoc/inara/the JOSS platform left a lot to be desired

@cthoyt.scholar.social.ap.brid.gySep 22, 2026, 10:08 AM

there's an unfortunate conflict between open science (I can participate in discussion and contribute to code on a centralized platform like GitHub) and sovereign science (I can't easily contribute or meet people on internal platforms like institutional GitLab instances) anyway, my EBI GitLab […]

@cthoyt.scholar.social.ap.brid.gySep 21, 2026, 6:13 PM

@niklaskorz feels like something that would get listed on @bonnjetzt

@cthoyt.scholar.social.ap.brid.gySep 20, 2026, 3:47 PM

[Fires of December spoilers]

do you think that the sixth word is related to the dawnshard(s?) that Hoid held?

#cosmere #sanderson

@cthoyt.scholar.social.ap.brid.gySep 18, 2026, 8:44 AM

@egonw lol

@cthoyt.scholar.social.ap.brid.gySep 4, 2026, 7:22 PM

blogged today about ChEBI, data properties in OWL ontologies, computational chemistry, atomic numbers, and basis sets

https://cthoyt.com/2026/09/04/chebi-atomic-numbers.html

all part of @NFDI4Chem, now onto a weekend full of dancing πŸ’ƒ

#obo #owl #chebi #obofoundry #nfdi #nfdi4chem #biocuration

@cthoyt.scholar.social.ap.brid.gySep 4, 2026, 11:22 AM

a semantic web-heavy paper that declares a prefix map in its appendix! very cool!

https://www.sciencedirect.com/science/article/pii/S2666546824000429

@cthoyt.scholar.social.ap.brid.gySep 4, 2026, 9:54 AM

i'm signing off pull requests with this from now on:

πŸ«€ No generative artificial intelligence was used to produce the code and text for this contribution; only human intelligence

anyone have ideas on how to make this text better?

#opensource #openscience #python #github #git #software […]

@cthoyt.scholar.social.ap.brid.gyAug 31, 2026, 8:23 PM

like any sane person, I auto-formatted the code before. and they added in a spurious space while editing the variable names. stay safe out there

@cthoyt.scholar.social.ap.brid.gyAug 31, 2026, 8:22 PM

i submitted a beautiful, hand-crafted PR with good variable names, which got merged, then the maintainers updated it in a follow-up to change the variable names to be cryptic. crazy times we live in

@cthoyt.scholar.social.ap.brid.gyAug 28, 2026, 10:47 AM

RE: https://mastodon.social/@andrewnez/117172702770260949

lincoln, nebraska got me

https://xkcd.com/2347/

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