@barcelonabeta.bsky.social
Research centre of @fpmaragall.bsky.social, pioneer in the study and prevention of Alzheimer's and other neurodegenerative diseases.
@caixaresearch.bsky.socialReposted by @barcelonabeta.bsky.social1/ 🧠 La mayoría de las personas con Alzheimer son mujeres, pero todavía no entendemos por qué.
¿Puede la historia reproductiva aportar nuevas pistas?
Hablamos con @clara-gallay.bsky.social, investigadora del @barcelonabeta.bsky.social, sobre qué nos dice la ciencia hasta ahora. 🎥👇
@barcelonabeta.bsky.social🌍 Air pollution is a modifiable risk factor for dementia. Reducing exposure to polluted air could help protect brain health and support dementia prevention.
The study adds to growing evidence of the potential impact of air quality on the brain.
@barcelonabeta.bsky.social🧪 Researchers also found sex-related differences in IL-6, a marker involved in inflammatory processes. In women, increased GFAP levels partially explained the association between air pollution exposure and declines in attention and executive function.
@barcelonabeta.bsky.social🔬 The study followed 226 cognitively unimpaired participants from the ALFA+ cohort over three years. Greater exposure to traffic-related air pollution was associated with increases in GFAP, a biomarker of astrocyte reactivity in the brain.
@barcelonabeta.bsky.social🧠 A study led by Dr. @natvilortejedor.bsky.social, from BBRC, links air pollution to early signs of neuroinflammation in people at risk of Alzheimer’s disease, particularly in women. The findings highlight the importance of understanding how environmental factors may affect brain health.
@barcelonabeta.bsky.socialTwo missions to discover what happens in the brain as the disease develops and to understand why Alzheimer’s is a multifactorial disease.
An experience to discover the challenges that research still faces.
🔗 More information:
www.barcelonabeta.org/en/news/news...
@barcelonabeta.bsky.social
@barcelonabeta.bsky.socialTo advance research in neurodegenerative diseases, we need to ensure clinical trials are as efficient as possible. Yesterday, we shared the work of our Clinical Operations Facility with Roche to continue exploring new avenues for collaboration. 🧠🔬
@barcelonabeta.bsky.social🔔 This Saturday, we’ll be at the #OpenPRBB!
@prbb.org
Don’t miss our activity, “Journey To The Brain: Exploring a New Dimension of Alzheimer’s”, and discover more about Alzheimer’s research. 🧠
🎟️ Book your place! www.prbb.org/openprbb?utm...
@barcelonabeta.bsky.socialReposted by @barcelonabeta.bsky.social🧠 BBRC & @fpmaragall.bsky.social will be one of the stops on the scientific route, with the activity “Journey To The Brain: Exploring a New Dimension of Alzheimer’s.” Two interactive missions to explore the brain at a cellular level and discover how research and prevention help tackle Alzheimer’s.
@barcelonabeta.bsky.social🍹 Don’t miss the Vermut Científic, a relaxed conversation about the future of biomedicine, moderated by science communicator Pere Estupinyà.
🎟️ See all the activities at the #OpenPRBB and book your place!
@barcelonabeta.bsky.social🧠 BBRC & @fpmaragall.bsky.social will be one of the stops on the scientific route, with the activity “Journey To The Brain: Exploring a New Dimension of Alzheimer’s.” Two interactive missions to explore the brain at a cellular level and discover how research and prevention help tackle Alzheimer’s.
@barcelonabeta.bsky.social1/3
🔜 Next Saturday, October 3rd, @prbb.org opens its doors again for the #OpenPRBB, this year celebrating its 20th anniversary!
Step inside the PRBB and discover the research carried out by its different centers. Visit labs, meet researchers and take part in interactive experiences.
@barcelonabeta.bsky.social🧠 Dr @gsalvado.bsky.social, group leader at BBRC, and Dr. Andreea Larisa (UB) will explore “#Alzheimer’s: The Brain’s Defences, a New Therapeutic Target” as part of “The Invisible Revolution session” to explore other cell types involved in the disease.
@barcelonabeta.bsky.social🔬 This Friday, September 25, we’re back at #ResearchersNight at Cosmo Caixa organised by @caixaresearch.bsky.social.
A night to discover, explore and interact with science! Meet researchers and enjoy talks, workshops, and activities for all audiences.
And we’ll be there! 👇
@barcelonabeta.bsky.socialThe study is the result of an international collaboration with Altoida, Sant Pau Memory, Hospital Clínic, BBRC & other partners.
🔗 alz-journals.onlinelibrary.wiley.com/doi/10.1002/...
Research continues to further investigate how cognitive and biological markers can be combined in AD.
@barcelonabeta.bsky.socialThe researchers also modeled a two-step approach combining digital cognitive screening with plasma p-tau217. In this model, pre-screening increased the positive predictive value of p-tau217 from 81.7% to 95.3%, while reducing the number requiring blood testing.
@barcelonabeta.bsky.socialParticipants from BBRC’s β-AARC research cohort contributed to this international study, alongside cohorts and clinical sites from Australia, Barcelona and the US. The work brings together expertise in digital cognition, clinical assessment and blood-based biomarkers.
@barcelonabeta.bsky.socialIn 688 participants across Australia, Spain and the US, the Altoida NeuroMarker identified mild cognitive impairment (MCI) with a ROC-AUC of 0.89. Digitally identified cognitive impairment was also significantly associated with elevated plasma p-tau217.
@barcelonabeta.bsky.social🧠New research involving BBRC explores how digital cognitive assessment and plasma p-tau217 may provide complementary information on cognition and #Alzheimer’s disease biology.
A thread on the new study published in @alzdemjournals.bsky.social👇
