Among older adults, #ADHD was associated with increased risk of later mild cognitive impairment or dementia, and higher genetic liability was also associated with greater risk.

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💬 Viewpoint: For older adults in Africa, voice-first #MentalHealth care may better match routine phone use and literacy realities than app-based or text-based services.

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💬 Viewpoint: For older adults in Africa, voice-first #MentalHealth care may better match routine phone use and literacy realities than app-based or text-based services.

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Among older adults, #ADHD was associated with increased risk of later mild cognitive impairment or dementia, and higher genetic liability was also associated with greater risk.

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Developmental changes in GRIN2A expression may help explain the timing of psychosis in #Schizophrenia and support stage-specific and genetically informed treatment approaches. ja.ma/4yvYbz6

A context-sensitive road map for #MentalHealth system scale-up indicates that governance, supervision, referral pathways, monitoring, and local adaptation are necessary for sustainable implementation. ja.ma/4hqhhyY

US #MentalHealth and #SubstanceUseDisorder expenditures totaled $174 billion in 2021-2023, or 7.0% of all medical spending, with ambulatory services accounting for the largest share. ja.ma/4hmVBFt

Maternal #PlacentalGrowthFactor trajectories diverged in the third trimester in pregnancies where children were later diagnosed with #ADHD, while endothelin-1 did not differ. ja.ma/4yPn6wW

💬 Viewpoint: In #Psychiatry, care for #Deaf and hard-of-hearing patients requires clinical competency because hearing loss, signed language, and social bluffing can complicate the Mental Status Examination and affect diagnosis. ja.ma/47cOyJh

💬 Viewpoint: A special collection in #Psychiatry highlights early-career investigators studying clinical equity, structural #MRI and machine learning, ultraprocessed foods and depression, and placental growth factor trajectories. ja.ma/4rrJolZ

Structural #MRI with machine learning estimated individual delay discounting in college-aged participants, with white matter volumes showing stronger performance than gray matter volumes. ja.ma/3TMXbXY

In patients with #Depression and high #UltraprocessedFoods intake, a low-ultraprocessed-food diet was feasible and acceptable, and depressive and anxiety symptoms were lower during the intervention period vs a regular diet. ja.ma/4xIUhBI

Interview with Laura Fässler, MSc, author of Psychological Interventions Targeting Auditory Hallucinations in Persons With Psychotic Disorders: A Systematic Review and Meta-Analysis. Hosted by John Torous, MD. ja.ma/4romkoa

Many studies using #Neurodivergent or #Neurodiverse terminology identified participants through self-report or self-identification, and some did not specify any diagnosis. Precise diagnostic descriptors may improve clinical research and practice.

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📝 Viewpoint: #Cannabis commercialization is a modifiable public health exposure shaped by policies on access, potency, labeling, and marketing. Regulating these features may reduce psychiatric risk beyond legalization status alone. 10.1001/jamapsychiatry.2026.2869

📝 Viewpoint: High-dose #psychedelic #clinicaltrials remain poorly masked, which limits isolation of pharmacological effects from expectancy effects.

More aggressive active comparators and reduced disclosure may strengthen causal inference.

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Among women with #BulimiaNervosa, structural #MRI identified lower nucleus accumbens volume and lower temporal cortical surface area vs healthy control individuals, supporting altered reward and social cognition circuits.

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In a Danish cohort, parental similarity for #PsychiatricDisorders was substantial and was associated with higher prevalence and higher family-based heritability than expected under random mating.

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💬 Viewpoint: In #Psychiatry, large language models should be used as clinical instruments, with clinician accountability and source-grounded verification before output influences care.

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💡 Special Communication: In psychiatry, #PolygenicScores, rare variant testing, and #Pharmacogenomics may have value when used selectively to inform diagnosis, prognosis, monitoring, and medication safety rather than population-wide screening.

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